By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on Life Science Research are presented in a new report. According to news reporting out of Madison, Wisconsin, by NewsRx editors, research stated, "Functionalized nano-graphene- and graphene-based nanocomposites have gained tremendous attention in the area of biomedicine in recent years owing to their biocompatibility, the ease with which they can be functionalized and their properties such as thermal and electrical conductivity. Potential applications for functionalized nanoparticles range from drug delivery and multimodal imaging to exploitation of the electrical properties of graphene toward the preparation of biosensing devices."
Our news journalists obtained a quote from the research from the University of Wisconsin, "This protocol covers the preparation, functionalization and bioconjugation of various graphene derivatives and nanocomposites. Starting from graphite, the preparations of graphene oxide (GO), reduced GO (RGO) and magnetic GO-based nanocomposite, as well as how to functionalize them with biocompatible polymers such as polyethylene glycol (PEG), are described in detail. We also provide procedures for I-125 radiolabeling of PEGylated GO and the preparation of GO-based gene carriers; other bioconjugation approaches including drug loading, antibody conjugation and fluorescent labeling are similar to those described previously and used for bioconjugation of PEGylated carbon nanotubes. We hope this article will help researchers in this field to fabricate graphene-based bioconjugates with high reproducibility for various applications in biomedicine."
According to the news editors, the research concluded: "The sample preparation procedures take various times ranging from 1 to 2 d."
For more information on this research see: Preparation and functionalization of graphene nanocomposites for biomedical applications. Nature Protocols, 2013;8(12):2392-2403. Nature Protocols can be contacted at: Nature Publishing Group, Macmillan Building, 4 Crinan St, London N1 9XW, England. (Nature Publishing Group - www.nature.com/; Nature Protocols - www.nature.com/nprot/)
Our news journalists report that additional information may be obtained by contacting K. Yang, University of Wisconsin, Carbone Canc Center, Madison, WI, United States. Additional authors for this research include L.Z. Feng, H. Hong, W.B. Cai and Z. Liu (see also Life Science Research).
Keywords for this news article include: Madison, Wisconsin, United States, Life Science Research, North and Central America
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