By a News Reporter-Staff News Editor at Biotech Week -- Investigators discuss new findings in Digestive System Diseases and Conditions. According to news reporting from Wuhan, People's Republic of China, by NewsRx journalists, research stated, "PurposeTo compare the characteristics of magnetic resonance perfusion-weighted imaging (MRPWI) scans before and after transcatheter arterial chemoembolization (TACE) treatment of hepatocellular carcinoma (HCC) and to apply MRPWI in evaluating the therapeutic effect of TACE and prognosis of HCC.Materials and methodsThirty-five patients with HCC undergoing their first TACE treatment were enrolled in this study. T2WI, T1WI, and PWI of MRI were performed 24-48 h before TACE and 48-168 h after TACE."
The news correspondents obtained a quote from the research from the Huazhong University of Science and Technology, "Perfusion parameters calculated with the maximum slope were used to create a time-signal intensity curve (TSC). The efficacy of TACE treatment in HCC was evaluated by examining the hemodynamic changes in TSC caused by TACE treatment.ResultsTSC before TACE showed a pattern of a quick decrease and a slow increase in the tumor region of interest in 34 patients with HCC, whereas the TSC for normal liver tissues showed a pattern of slow decrease and slow increase. After TACE, the fluctuating range of TSC was significantly reduced in 31 patients, slightly reduced in three, and did not change significantly in one. The 3-year survival rate was 28.6%.ConclusionMRPWI of the liver does not only show the anatomy of HCC lesions but also reflects hemodynamic changes of HCC before and after TACE to a certain extent."
According to the news reporters, the research concluded: "It is very useful for clinical evaluation of the efficacy of TACE for HCC."
For more information on this research see: Evaluating the therapeutic effect of hepatocellular carcinoma treated with transcatheter arterial chemoembolization by magnetic resonance perfusion imaging. European Journal of Gastroenterology & Hepatology, 2014;26(1):109-113. European Journal of Gastroenterology & Hepatology can be contacted at: Lippincott Williams & Wilkins, 530 Walnut St, Philadelphia, PA 19106-3621, USA. (Lippincott Williams and Wilkins - www.lww.com; European Journal of Gastroenterology & Hepatology - journals.lww.com/eurojgh/pages/default.aspx)
Our news journalists report that additional information may be obtained by contacting X.Y. Chen, Huazhong University of Science & Technology, Dept. of Radiol, Union Hosp, Tongji Med College, Wuhan 430074, Hubai, People's Republic of China. Additional authors for this research include E.H. Xiao, D.S. Shu, C.Z. Yang, B. Liang, Z. He and D.J. Bian (see also Digestive System Diseases and Conditions).
Keywords for this news article include: Asia, Wuhan, Therapy, Oncology, Treatment, Magnetic Resonance, Hepatocellular Carcinoma, People's Republic of China, Digestive System Diseases and Conditions
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC