By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators discuss new findings in Fibroblasts. According to news reporting originating from Inchon, South Korea, by NewsRx correspondents, research stated, "Several natural bioactive molecules have been used in the development of scaffolds to enhance biocompatibility or biodegradability and macroalgae contain many bioactive compounds that regulate the physiological activities of cells. In this study, extrapolymeric substances (EPS) from brown algae, Undaria pinnatifida, were dispersed in poly-epsilon-caprolactone (PCL) nanofiber, fabricated by electrospinning technique to mimic natural extracellular matrix (ECM), and tested as a scaffold for the production of artificial skin using rat primary fibroblasts."
Our news editors obtained a quote from the research from Inha University, "The level of adhesion, viability, and infiltration of cells on the EPS-PCL nanofibers were then assessed. The primary fibroblasts attached well, had good viability, and infiltrated through the nanofiber mat without cytotoxicity. Additionally, fibroblast on EPS-PCL nanofiber overcame the stress derived from high cell density at limited area."
According to the news editors, the research concluded: "These results indicate that EPS-imbedded nanofiber has the potential to be used as scaffolds to develop artificial skin or as wound-healing nanomedicines to regenerate injured skin."
For more information on this research see: Evaluation of EPS-PCL Nanofibers as a Nanobiocomposite for Artificial Skin Based on Dermal Fibroblast Culture. Journal of Nanomaterials, 2013;():1-6. Journal of Nanomaterials can be contacted at: Hindawi Publishing Corporation, 410 Park Avenue, 15TH Floor, #287 Pmb, New York, NY 10022, USA. (Hindawi Publishing - www.hindawi.com; Journal of Nanomaterials - www.hindawi.com/journals/jnm/)
The news editors report that additional information may be obtained by contacting S.M. Jung, Inha University, Dept. of Biol Engn, Inchon 402751, South Korea. Additional authors for this research include D.S. Kim, J.H. Ju and H.S. Shin (see also Fibroblasts).
Keywords for this news article include: Asia, Inchon, Nanofiber, South Korea, Fibroblasts, Nanotechnology, Emerging Technologies, Connective Tissue Cells
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