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Findings in General Science Reported from National Institute of Advanced Industrial Science and Technology (NIAIST)

February 7, 2014

By a News Reporter-Staff News Editor at Science Letter -- Current study results on Science have been published. According to news originating from Ibaraki, Japan, by NewsRx correspondents, research stated, "Surface plasmon excitation provides stronger enhancement of the fluorescence intensity and better sensitivity than other sensing approaches but requires optimal positioning of a prism to ensure optimum output of the incident light. Here we describe a simple, highly sensitive optical sensing system combining surface plasmon excitation and fluorescence to address this limitation."

Our news journalists obtained a quote from the research from the National Institute of Advanced Industrial Science and Technology (NIAIST), "V-shaped fluidic channels are employed to mimic the functions of a prism, sensing plate, and flow channel in a single setup. Superior performance is demonstrated for different biomolecular recognition reactions on a self-assembled monolayer, and the sensitivity reaches 100 fM for biotin-streptavidin interactions. Using an antibody as a probe, we demonstrate the detection of intact influenza viruses at 0.2HA units ml(-1) levels."

According to the news editors, the research concluded: "The convenient sensing system developed here has the advantages of being prism-free and requiring less sample (1-2 mu l), making this platform suitable for use in situations requiring low sample volumes."

For more information on this research see: An angular fluidic channel for prism-free surface-plasmon-assisted fluorescence capturing. Nature Communications, 2013;4():10-16. Nature Communications can be contacted at: Nature Publishing Group, Macmillan Building, 4 Crinan St, London N1 9XW, England. (Nature Publishing Group -; Nature Communications -

The news correspondents report that additional information may be obtained from K. Nomura, Natl Inst Adv Ind Sci & Technol, Nanoelect Res Inst, Tsukuba, Ibaraki 3058562, Japan. Additional authors for this research include S.C.B. Gopinath, T. Lakshmipriya, N. Fukuda, X.M. Wang and M. Fujimaki (see also Science).

Keywords for this news article include: Asia, Japan, Ibaraki, Science

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Source: Science Letter

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