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Studies from National Taiwan University Add New Findings in the Area of Aspergillus

February 7, 2014

By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Aspergillus have been published. According to news reporting originating in Taipei, Taiwan, by NewsRx journalists, research stated, "In the present study, black soybeans were fermented with Aspergillus awamori at 30C for 3 days. The effect of fermentation on the antiproliferative effect against human colon cancer cells, Caco-2 and HT-29 as well as Cu(2+)-chelating effect of black soybeans was investigated."

The news reporters obtained a quote from the research from National Taiwan University, "It was found that the water, 80% methanol or 80% ethanol extract of fermented black soybeans showed a significantly higher (P < 0.05) antiproliferative and Cu(2+)-chelating effect than did the respective extract of non-fermented black soybeans. Generally, the methanol extract and the ethanol extract of fermented black soybeans exerted higher antiproliferative effect on both Caco-2 and HT-29 cells. While water extract of fermented black soybeans showed the highest Cu(2+)-chelating effect among the various extracts examined. Taking into account of extraction yields further revealed that bioactive principles that exhibit Cu(2+)-chelating effect could be extracted to the largest extent with water as the extraction solvent."

According to the news reporters, the research concluded: "With same amount of sample, water extract obtained from fermented black soybeans possesses the highest Cu(2+)-chelating abilities."

For more information on this research see: Enhancing the antitumor cell proliferation and Cu(2+)-chelating effects of black soybeans through fermentation with Aspergillus awamori. Journal of Bioscience and Bioengineering, 2013;115(4):400-4. (Elsevier -; Journal of Bioscience and Bioengineering -

Our news correspondents report that additional information may be obtained by contacting Y.F. Chen, Graduate Institute of Food Science and Technology, National Taiwan University, Taipei, Taiwan. Additional authors for this research include M.L. Chiang, C.C. Chou and Y.C Lo (see also Aspergillus).

Keywords for this news article include: Asia, Taipei, Taiwan, Aspergillus, Cell Proliferation.

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Source: Health & Medicine Week

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