By a News Reporter-Staff News Editor at Health & Medicine Week -- Researchers detail new data in Pathology. According to news reporting from New York City, New York, by NewsRx journalists, research stated, "To evaluate in vivo epithelial thickness in dry eye by anterior segment optical coherence tomography. Observational, retrospective case-control study."
The news correspondents obtained a quote from the research from New York University, "Two age-matched groups of female subjects, 70 eyes each, age approximate to 55 years, were studied in clinical practice setting: a control (unoperated, no ocular pathology) and a dry eye group (clinically confirmed dry eye, unoperated and no other ocular pathology). Corneal epithelium over the entire cornea was topographically imaged via, a novel anterior segment optical coherence tomography (AS-OCT) system. Average, central, and peripheral epithelial thickness as well as topographic epithelial thickness variability were measured. For the control group, central epithelial thickness was 53.0 +/- 2.7 mu m (45-59 mu m). Average epithelium thickness was 53.3 +/- 2.7 mu m (46.7-59.6 mu m). Topographic thickness variability was 1.9 +/- 1.1 mu m (0.7-6.1 mu m). For the dry eye group, central epithelial thickness was 59.5 +/- 4.2 mu m (50-72 mu m) and average thickness was 59.3 +/- 3.4 mu m (51.4-70.5 mu m). Topographic thickness variability was 2.5 +/- 1.5 mu m (0.9-6.9 mu m). All pair tests of respective epithelium thickness metrics between the control and dry eye group show statistically significant difference (P < .05). This study, based on very user-friendly, novel AS-OCT imaging, indicates increased epithelial thickness in dry eyes. The ease of use and the improved predictability offered by AS-OCT epithelial imaging may be a significant clinical advantage."
According to the news reporters, the research concluded: "Augmented epithelial thickness in the suspect cases may be employed as an objective clinical indicator of dry eye."
For more information on this research see: In Vivo 3-Dimensional Corneal Epithelial Thickness Mapping as an Indicator of Dry Eye: Preliminary Clinical Assessment. American Journal of Ophthalmology, 2014;157(1):63-68. American Journal of Ophthalmology can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; American Journal of Ophthalmology - www.elsevier.com/wps/product/cws_home/601028)
Our news journalists report that additional information may be obtained by contacting A.J. Kanellopoulos, New York University, Sch Med, New York, NY 10012, United States (see also Pathology).
Keywords for this news article include: Pathology, New York City, United States, North and Central America
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