When animal models were injected with IMPs after a heart attack, the size of the heart lesions were reduced by 50 percent allowing the heart to pump significantly more blood. IMP treatment showed reduced inflammation and promoted regeneration in all models tested.
"This is the first therapy that specifically targets a key driver of the inflammation that occurs after a heart attack," said
Originally discovered in the laboratory of Professor
"IMP therapy represents a significant step toward the next generation of immune modulating agents," said
The therapy also showed efficacy in numerous other inflammatory models, specifically in West Nile Virus, Encephalitis, Peritonitis, Multiple Sclerosis, and Inflammatory Bowel Disease - all with the potential to benefit patients suffering from these inflammatory diseases.
Getts and King are corresponding authors on the paper, which was published
For more information, visit www.courpharma.com
Keywords for this news article include: Therapy, Cardiology, Heart Attack.
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