By a News Reporter-Staff News Editor at Clinical Trials Week -- A new study on Macromolecular Research is now available. According to news reporting from Davis, California, by NewsRx journalists, research stated, "Complementary interactions between functionalized surfaces are challenging to quantify, as both kinetics and thermodynamics are important. Optimal reaction parameters are key to the efficient formation of hierarchical nanostructures."
The news correspondents obtained a quote from the research from the University of California, "Here, we report both surface forces apparatus (SFA) studies and molecular dynamics (MD) simulations of the controlled binding of thiol functionalized polymer brushes to complementary gold surfaces. Polymer brush brush, brush mica, and brush gold experiments were performed in toluene. These comparative studies reveal the subtle balance of nonspecific and specific contributions to the measured interactions. Importantly, the physical phenomena responsible for the measured force profile in the selective binding system, including the formation of thiol gold bonds, the resulting adhesion between the surfaces, the work to separate the surfaces, and the anchor strength of the polymer brush can be extracted. Corroborating MD simulations demonstrate that hysteresis in the approach and separation of these selectively bound surfaces is not the result of kinetic effects, but rather is due to the polydispersity of the brush itself and the resulting thiolated chain end distribution."
According to the news reporters, the research concluded: "We relate our findings to observations made in the formation of hierarchical particle aggregates."
For more information on this research see: Using Thiol-Gold Bond Formation To Bridge Surfaces with a Polymer Brush: SFA Experiments and MD Simulations. Macromolecules, 2013;46(24):9826-9836. Macromolecules can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Macromolecules - www.pubs.acs.org/journal/mamobx)
Our news journalists report that additional information may be obtained by contacting S.M. Balko, University of California, Dept. of Chem, Davis, CA 95616, United States. Additional authors for this research include T. Kreer, D.J. Mulder, P.J. Costanzo, T.E. Patten and T.L. Kuhl (see also Macromolecular Research).
Keywords for this news article include: Davis, California, United States, Macromolecular Research, North and Central America, Clinical Trials and Studies
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC