By a News Reporter-Staff News Editor at Health & Medicine Week -- New research on Eye Diseases and Conditions is the subject of a report. According to news reporting from Mannheim, Germany, by NewsRx journalists, research stated, "To examine the features of myopia-related optical coherence tomography (OCT) findings in a population-based setting. Population-based study. The Beijing Eye Study 2011 included 3468 subjects with an age of 50 years or more."
The news correspondents obtained a quote from the research from the University of Heidelberg, "The participants underwent a detailed ophthalmic examination including OCT with enhanced depth imaging of the macula. Optical coherence tomography features of the macula in highly myopic eyes defined by a refractive error of -6 diopters or less or an axial length of 26.5 mm or more. Readable OCT images were available for 6530 eyes (94.5%) of 3278 participants. The most common change in the macula was maculoschisis (0.8 +/- 0.1%), followed by incomplete posterior vitreous detachment (0.7 +/- 0.1%), disruption of the photoreceptor inner segment/ outer segment interface (0.6 +/- 0.1%), epiretinal membranes (0.6 +/- 0.1%), macular defects in Bruch's membrane (0.3 +/- 0.1%), clumping of the retinal pigment epithelium (0.2 +/- 0.1%), vitreofoveal adhesion (0.2 +/- 0.1%), and macular holes in 2 eyes (0.1 +/- 0.1%). Prevalence of any myopic maculopathy per eye was 112 of 6530, or 1.71 +/- 0.16% (95% confidence interval [ CI], 1.40e2.03). After adjustment for longer axial length (P < 0.001; odds ratio [ OR], 2.68; 95% CI, 1.97e3.64) and myopic refractive error (P < 0.001; OR, 0.63; 95% CI, 0.55e0.73), presence of any myopic maculopathy was not significantly associated with any systemic variables (all P< 0.05), including biochemical blood examination and ocular parameters. Best-corrected visual acuity was associated significantly with the absence of a disruption of the photoreceptor inner segment/outer segment interface (P < 0.001), epiretinal membranes (P < 0.001), and macular holes (P < 0.001) after adjustment for age and cylindrical refractive error. Based on OCT examination, the most common macular change in highly myopic eyes was maculoschisis, followed by incomplete posterior vitreous detachment, disruption of the photoreceptor inner segment/ outer segment interface, epiretinal membranes, macular defects in Bruch's membrane, clumping of the retinal pigment epithelium, vitreofoveal adhesion, and macular holes."
According to the news reporters, the research concluded: "The most important macular changes with a negative effect on best-corrected visual acuity were a disruption of the photoreceptor inner segment/outer segment interface and epiretinal membranes."
For more information on this research see: Myopic Maculopathy Imaged by Optical Coherence Tomography The Beijing Eye Study. Ophthalmology, 2014;121(1):220-224. Ophthalmology can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; Ophthalmology - www.elsevier.com/wps/product/cws_home/620418)
Our news journalists report that additional information may be obtained by contacting Q.S. You, Heidelberg Univ, Medical Fac Mannheim, Dept. of Ophthalmol, Mannheim, Germany. Additional authors for this research include X.Y. Peng, L. Xu, C.X. Chen, Y.X. Wang and J.B. Jonas (see also Eye Diseases and Conditions).
Keywords for this news article include: Europe, Germany, Mannheim, Retinal Diseases, Refractive Errors, Imaging Technology, Epiretinal Membrane, Eye Diseases and Conditions, Optical Coherence Tomography
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