ENP Newswire -
Release date- 22012014 -
OxSonics, set up last July by the University's technology transfer company Isis Innovation, has raised
Lead researcher and OxSonics co-founder Professor
'Ultrasound is best known for its diagnostic capabilities. For drug delivery, we will be using similar power settings to those used for conventional imaging applications.'
In a study published in the
'A particular type of ultrasound-induced bubble activity, known as inertial cavitation, was found to be key - as bubbles collapse, they agitate the fluid around them, pumping anti-cancer drugs deeper into the tumours than ever previously reported,' said Professor Coussios.
Compared to drug treatment without ultrasound, the team found that cavitation-enhanced delivery significantly hindered tumour growth and increased the survival rates of the mice being studied.
'Ultrasound can dramatically enhance delivery of drugs, particularly for next-generation therapeutics such as immune therapies or virotherapies,' said Professor Coussios. 'This focuses drug treatment at the site of the tumour, potentially reducing or avoiding damage to other parts of the body, a hazard associated with the use of chemotherapy drugs.'
'OxSonics technology can safely deliver drugs to the whole tumour, rather than a small portion of it. Our mission is to provide curative therapy to those patients who would otherwise be faced with a terminal illness.'
The company will also adapt the very same ultrasound technology, at a higher power setting, to surgically treat chronic lower back pain by repairing intervertebral discs. Lower back pain is one of the most common health problems in the developed world, affecting over 80 per cent of adults at some point in their life. OxSonics' minimally invasive surgical approach could provide an alternative to highly invasive procedures such a spinal fusion.
The syndicated investment, led by
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