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Researchers from Sharif University of Technology Describe Findings in Lidocaine Therapy

January 29, 2014

By a News Reporter-Staff News Editor at Biotech Week -- New research on Drugs and Therapies is the subject of a report. According to news reporting out of Tehran, Iran, by NewsRx editors, research stated, "A glassy carbon electrode (GCE) is modified with platinum nanoparticle (PtNPs) decorated multiwalled carbon nanotube (MWCNT). The modified electrode is applied for the determination of ceftriaxone (CFX) in the presence of lidocaine."

Our news journalists obtained a quote from the research from the Sharif University of Technology, "Different methods were used to characterize the surface morphology of the modified electrode. The electrochemical behavior of CFX was investigated at GCE, MWCNT/GCE and PtNPs/MWCNT/GCE. A factorial-based response-surface methodology was used to find out the optimum conditions with minimum number of experiments. Under the optimized conditions, oxidation peak currents increased linearly with CFX concentration in the range of 0.01-10.00 mu M with a detection limit of 9.01 nM."

According to the news editors, the research concluded: "The results prove that the modified electrode is also suitable for the determination of CFX in pharmaceutical and clinical preparations."

For more information on this research see: Fabrication of an electrochemical sensor based on the electrodeposition of Pt nanoparticles on multiwalled carbon nanotubes film for voltammetric determination of ceftriaxone in the presence of lidocaine, assisted by factorial-based response-surface. Journal of Solid State Electrochemistry, 2014;18(1):77-88. Journal of Solid State Electrochemistry can be contacted at: Springer, 233 Spring St, New York, NY 10013, USA. (Springer -; Journal of Solid State Electrochemistry -

Our news journalists report that additional information may be obtained by contacting S. Shahrokhian, Sharif Univ Technol, Inst Nanosci & Technol, Tehran 111559516, Iran. Additional authors for this research include N. Hosseini-Nassab and Z. Kamalzadeh (see also Drugs and Therapies).

Keywords for this news article include: Iran, Asia, Antiarrhythmic Agents, Pharmaceuticals, Tehran, Chemistry, Lidocaine, Thiazines, Cefotaxime, Fullerenes, Ceftriaxone, Acetanilides, Nanoparticle, Cephalosporins, Nanotechnology, Topical Agents, Electrochemical, Sulfur Compounds, Drugs and Therapies, Cardiovascular Agents, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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