News Column

New Findings on Brain Research Described by Investigators at Korea Institute of Science and Technology

January 31, 2014

By a News Reporter-Staff News Editor at Drug Week -- Current study results on Brain Research have been published. According to news reporting out of Seoul, South Korea, by NewsRx editors, research stated, "The development of drugs to treat disorders of the central nervous system (CNS) faces difficulties in achieving penetration of a drug through the blood-brain barrier (BBB) and allowing the drug to reach its intended target in the brain. There have been strategies to improve drug delivery to the brain through endogenous transport pathways such as passive diffusion, endocytosis, and active transport."

Our news journalists obtained a quote from the research from the Korea Institute of Science and Technology, "Among various strategies, nano-enabled delivery systems offer a promising solution to improve the uptake and targeted delivery of drugs into the brain. Various nanocarriers including liposomes, bolaamphiphiles and nanoparticles can be used as a means to encapsulate drugs, either alone or in combination with targeting ligands. Moreover, most of materials used in nanocarrier fabrication are both biodegradable and biocompatible, thereby increasing the clinical utility of them."

According to the news editors, the research concluded: "Here, we review the possibility to employ nano-enabled materials for delivery of drug across the BBB and the recent advances in nanotechnologies for therapy of the CNS diseases."

For more information on this research see: Nano-enabled delivery systems across the blood-brain barrier. Archives of Pharmacal Research, 2014;37(1):24-30. Archives of Pharmacal Research can be contacted at: Pharmaceutical Soc Korea, 1489-3 Suhcho-Dong, Suhcho-Ku, Seoul 137-071, South Korea. (Springer -; Archives of Pharmacal Research -

Our news journalists report that additional information may be obtained by contacting S.R. Hwang, Korea Inst Sci & Technol, Center Theragnosis, Biomed Res Inst, Seoul 136791, South Korea (see also Brain Research).

Keywords for this news article include: Asia, Seoul, South Korea, Brain Research, Blood Brain Barrier, Blood-Brain Barrier

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Source: Drug Week

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