Our news journalists obtained a quote from the research, "We suggest that this may be a consequence of cells protecting their metabolism against stochastic fluctuations in expression as well as enabling a fast response for those fluxes that may need to be changed quickly. Furthermore, it is impossible for a regulatory program to guarantee optimal expression levels in all conditions."
According to the news editors, the research concluded: "Several studies have found examples of demonstrably suboptimal regulation of gene expression, and improvements to the regulatory network have been investigated in laboratory evolution experiments."
For more information on this research see: Somewhat in control - the role of transcription in regulating microbial metabolic fluxes. Current Opinion in Biotechnology, 2013;24(6):987-993. Current Opinion in Biotechnology can be contacted at:
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