News Column

New Endodontics Data Have Been Reported by Researchers at University of Toronto

January 31, 2014

By a News Reporter-Staff News Editor at Health & Medicine Week -- Data detailed on Dentistry have been presented. According to news reporting from Toronto, Canada, by NewsRx journalists, research stated, "The purpose of this study was to assess biofilm formation within sealer-dentin interfaces of root segments filled with gutta-percha and sealer incorporated with chitosan (CS) nanoparticles with and without canal surface treatment with different formulations of CS. Standardized canals of 4-mm bovine root segments (N=35) were filled with gutta-percha and pulp canal sealer incorporated with CS nanoparticles without surface treatment (group CS) or after surface treatment with phosphorylated CS (group PHCS), CS-conjugated rose bengal and photodynamic irradiation (group CSRB), or a combination of both PHCS and CSRB (group RBPH)."

The news correspondents obtained a quote from the research from the University of Toronto, "The control group was filled with gutta-percha and an unmodified sealer. After 7 days of setting, specimens were aged in buffered solution at 37C for 1 or 4 weeks. Monospecies biofilms of Enterococcus faecalis were grown on specimens for 7 days in a chemostat-based biofilm fermentor. Biofilm formation within the sealer-dentin interface was assessed with confocal laser scanning microscopy. In the 4-week-aged specimens only, the mean biofilm areas were significantly smaller than in the control for the CS (p=.008), PHCS (p=.012), and RBPH (p=.034) groups. The percentage of the biofilm-covered interface also was significantly lower than in the control for the CS (p=.024) and PHCS (p=.003) groups. The CS, PHCS, and RBPH groups did not differ significantly. Incorporating CS nanoparticles into the zinc oxide-eugenol sealer inhibited biofilm formation within the sealer-dentin interface."

According to the news reporters, the research concluded: "This effect was maintained when canals were treated with phosphorylated CS, and it was moderated by canal treatment with CS-conjugated rose bengal and irradiation."

For more information on this research see: Biofilm formation within the interface of bovine root dentin treated with conjugated chitosan and sealer containing chitosan nanoparticles. Journal of Endodontics, 2013;39(2):249-53. (Elsevier -; Journal of Endodontics -

Our news journalists report that additional information may be obtained by contacting L. DaSilva, Discipline of Endodontics, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada. Additional authors for this research include Y. Finer, S. Friedman, B. Basrani and A. Kishen (see also Dentistry).

Keywords for this news article include: Canada, Toronto, Ontario, Dentistry, Treatment, North and Central America.

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Source: Health & Medicine Week

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