News Column

Findings from Sun Yat Sen University Update Knowledge of Fibrin Tissue Adhesives

January 29, 2014

By a News Reporter-Staff News Editor at Biotech Week -- New research on Biomedicine and Biomedical Engineering is the subject of a report. According to news reporting originating from Guangdong, People's Republic of China, by NewsRx correspondents, research stated, "We evaluated the curative effect of fibrin glue combined with OK-432 (streptococcal pyrogenic exotoxin A, Picibanil ) and bleomycin on 9 patients with sialoceles after parotidectomy. The primary lesions included pleomorphic adenomas in 6 cases and Warthin's tumours in 3 cases."

Our news editors obtained a quote from the research from Sun Yat Sen University, "After a sialocele had been diagnosed each patient had repeated aspirations and pressure dressings for 3-4 weeks, but these treatments failed. The patients were then treated with percutaneous sclerotherapy with the injection of fibrin glue 8-10 ml combined with OK-432 5 mg and bleomycin 15 mg. All the sialoceles disappeared completely after a single procedure in 2-3 weeks. The patients have been followed up for more than 6 months with no evidence of recurrent sialocele or injury to the facial nerve related to sclerotherapy."

According to the news editors, the research concluded: "This simple, safe technique can be successfully used to treat sialoceles after parotidectomy."

For more information on this research see: Percutaneous sclerotherapy of sialoceles after parotidectomy with fibrin glue, OK-432, and bleomycin. British Journal of Oral & Maxillofacial Surgery, 2013;51(8):786-788. British Journal of Oral & Maxillofacial Surgery can be contacted at: Churchill Livingstone, Journal Production Dept, Robert Stevenson House, 1-3 Baxters Place, Leith Walk, Edinburgh EH1 3AF, Midlothian, Scotland. (Elsevier -; British Journal of Oral & Maxillofacial Surgery -

The news editors report that additional information may be obtained by contacting W.L. Chen, Sun Yat Sen UniversitySun Yat Sen Mem Hosp, Dept. of Oral & Maxillofacial Surg, Guangzhou 510120, Guangdong, People's Republic of China. Additional authors for this research include L.P. Zhang, Z.Q. Huang and B. Zhou (see also Biomedicine and Biomedical Engineering).

Keywords for this news article include: Asia, Tissue Engineering, Biomedicine and Biomedical Engineering, Guangdong, Sclerotherapy, Bioengineering, Blood Proteins, Fibrin Sealant, Medical Devices, People's Republic of China

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Source: Biotech Week

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