By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators discuss new findings in Eye Diseases and Conditions. According to news reporting out of Seoul, South Korea, by NewsRx editors, research stated, "BackgroundTo evaluate and compare the utility of ganglion cell complex with peripapillary retinal nerve fibre layer and optic nerve head measurements for detection of localized defects in patients with preperimetric glaucoma using spectral-domain optical coherence tomography. DesignProspective study. ParticipantsPreperimetric glaucoma patients. MethodsA total of 105 eyes with preperimetric glaucoma and 68 age- and refractive error-matched control eyes were enrolled."
Our news journalists obtained a quote from the research from the University of Ulsan, "The ability to detect localized retinal nerve fibre layer defects by RTVue-100 spectral-domain optical coherence tomography (Optovue, Inc., Fremont, CA, USA) was assessed calculating the areas under receiver operating characteristic curves. MeasuresThe ability to detect localized retinal nerve fibre layer defects by spectral-domain optical coherence tomography. ResultsGlobal volume loss and superior ganglion cell complex thickness showed the largest area under receiver operating characteristic curve values (both areas under receiver operating characteristic curves 0.84, P0.02). ConclusionsGanglion cell complex thickness was significantly reduced in eyes with preperimetric glaucoma."
According to the news editors, the research concluded: "Ganglion cell complex imaging using spectral-domain optical coherence tomography may be a useful ancillary modality for detection of early macular changes in glaucomatous eyes with localized retinal nerve fibre layer defects."
For more information on this research see: Detection of macular ganglion cell loss in preperimetric glaucoma patients with localized retinal nerve fibre defects by spectral-domain optical coherence tomography. Clinical and Experimental Ophthalmology, 2013;41(9):870-880. Clinical and Experimental Ophthalmology can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Clinical and Experimental Ophthalmology - onlinelibrary.wiley.com/journal/10.1111/(ISSN)1442-9071)
Our news journalists report that additional information may be obtained by contacting J.H. Na, University of Ulsan, Coll Med, Asan Med Center, Dept. of Clin Epidemiol & Biostat, Seoul 138736, South Korea. Additional authors for this research include K. Lee, J.R. Lee, S. Baek, S.J. Yoo and M.S. Kook (see also Eye Diseases and Conditions).
Keywords for this news article include: Asia, Seoul, Glaucoma, South Korea, Imaging Technology, Eye Diseases and Conditions, Optical Coherence Tomography
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