By a News Reporter-Staff News Editor at Insurance Weekly News -- Data detailed on Risk Management have been presented. According to news originating from Ottawa, Canada , by VerticalNews correspondents, research stated, "Some volatile N-nitrosamines, primarily N-nitrosodimethylamine (NDMA), are recognized as products of drinking water treatment at ng/L levels and as known carcinogens. The U.S. EPA has identified the N-nitrosamines as contaminants being considered for regulation as a group under the Safe Drinking Water Act." Our news journalists obtained a quote from the research, "Nitrosamines are common dietary components, and a major database (over 18,000 drinking water samples) has recently been created under the Unregulated Contaminant Monitoring Rule. A Monte Carlo modeling analysis in 2007 found that drinking water contributed less than 2.8% of ingested NDMA and less than 0.02% of total NDMA exposure when estimated endogenous formation was considered. Our analysis, based upon human blood concentrations, indicates that endogenous NDMA production is larger than expected. The blood-based estimates are within the range that would be calculated from estimates based on daily urinary NDMA excretion and an estimate based on methylated guanine in DNA of lymphocytes from human volunteers. Our analysis of ingested NDMA from food and water based on Monte Carlo modeling with more complete data input shows that drinking water contributes a mean proportion of the lifetime average daily NDMA dose ranging from between 0.0002% and 0.001% for surface water systems using free chlorine or between 0.001% and 0.01% for surface water systems using chloramines." According to the news editors, the research concluded: "The proportions of average daily dose are higher for infants (zero to six months) than other age cohorts, with the highest mean up to 0.09% (upper 95th percentile of 0.3%)." For more information on this research see: Drinking Water as a Proportion of Total Human Exposure to Volatile N-Nitrosamines. Risk Analysis , 2013;33(12):2179-2208. Risk Analysis can be contacted at: Wiley-Blackwell, 111 River St , Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/ ; Risk Analysis - onlinelibrary.wiley.com/journal/10.1111/ (ISSN)1539-6924) The news correspondents report that additional information may be obtained from S.E. Hrudey , Risk Sci Int, Ottawa, ON , Canada . Additional authors for this research include R.J. Bull , J.A. Cotruvo , G. Paoli and M. Wilson . Keywords for this news article include: Ottawa, Canada , Ontario , Risk Management, North and Central America Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
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