By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Proteobacteria are discussed in a new report. According to news reporting originating from Tamil Nadu, India, by NewsRx correspondents, research stated, "Pseudomonas aeruginosa PGPR2 was found to protect mungbean plants from charcoal rot disease caused by Macrophomina phaseolina. Secondary metabolites from the culture supernatant of P. aeruginosa PGPR2 were extracted with ethyl acetate and the antifungal compound was purified by preparative HPLC using reverse phase chromatography."
Our news editors obtained a quote from the research from Madurai Kamaraj University, "The purified compound showed antifungal activity against M. phaseolina and other phytopathogenic fungi (Fusarium sp., Rhizoctonia sp. Alternaria sp., and Aspergillus sp.). The structure of the purified compound was determined using H-1, C-13, 2D NMR spectra and liquid chromatography-mass spectrometry (LC-MS). Spectral data suggest that the antifungal compound is 3,4-dihydroxy-N-methyl-4-(4-oxochroman-2-yl)butanamide, with the chemical formula C14H17NO5 and a molecular mass of 279. Though chemically synthesized chromanone derivatives have been shown to have antifungal activity, we report for the first time, the microbial production of a chromanone derivative with antifungal activity."
According to the news editors, the research concluded: "This ability of P. aeruginosa PGPR2 makes it a suitable strain for biocontrol."
For more information on this research see: Identification and Structure Elucidation of a Novel Antifungal Compound Produced by Pseudomonas aeruginosa PGPR2 Against Macrophomina phaseolina. Applied Biochemistry and Biotechnology, 2013;171(8):2176-2185. Applied Biochemistry and Biotechnology can be contacted at: Humana Press Inc, 999 Riverview Drive Suite 208, Totowa, NJ 07512, USA. (Springer - www.springer.com; Applied Biochemistry and Biotechnology - www.springerlink.com/content/0273-2289/)
The news editors report that additional information may be obtained by contacting D. Illakkiam, Madurai Kamaraj Univ, Sch Chem, Dept. of Organ Chem, Madurai 625021, Tamil Nadu, India. Additional authors for this research include P. Ponraj, M. Shankar, S. Muthusubramanian, J. Rajendhran and P. Gunasekaran (see also Proteobacteria).
Keywords for this news article include: Asia, India, Tamil Nadu, Pseudomonadaceae, Gammaproteobacteria, Gram-Negative Bacteria, Pseudomonas aeruginosa, Gram-Negative Aerobic Bacteria, Gram-Negative Aerobic Rods and Cocci
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