By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Bacterial Infections have been published. According to news reporting originating in Quebec City, Canada, by NewsRx journalists, research stated, "Hydroxyapatite (HA) coated implant is more susceptible to bacterial infection as the micro-structure surface which is beneficial for osseointegration, could also become a reservoir for bacterial colonisation. The aim of this study was to introduce the antibacterial effect of silver (Ag) to the biomineralised HA by utilising a polydopamine film as an intermediate layer for Ag and HA immobilisation."
The news reporters obtained a quote from the research from Laval University, "Sufficient catechol groups in polydopamine were required to bind chemically stainless steel 316 L, Ag and HA elements. Different amounts of Ag nanoparticles were metallised on the polydopamine grafted stainless steel by varying the immersion time in silver nitrate solution from 12 to 24 h. Another polydopamine layer was then formed on the metallised film, followed by surface biomineralisation in 1.5 Simulated Body Fluid (SBF) solution for 3 days. Several characterisation techniques including X-Ray Photoelectron Spectroscopy, Atomic Force Microscopy, Scanning Electron Microscopy and Contact Angle showed that Ag nanoparticles and HA agglomerations were successfully immobilised on the polydopamine film through an element reduction process. The Ag metallisation at 24 h has killed the viable bacteria with 97.88% of bactericidal ratio. The Ag was ionised up to 7 days which is crucial to prevent bacterial infection during the first stage of implant restoration. The aged functionalised films were considered stable due to less alteration of its chemical composition, surface roughness and wettability properties."
According to the news reporters, the research concluded: "The ability of the functionalised film to coat complex and micro scale metal make it suitable for dental and orthopaedic implants application."
For more information on this research see: Polydopamine as an intermediate layer for silver and hydroxyapatite immobilisation on metallic biomaterials surface. Materials Science & Engineering C-Materials for Biological Applications, 2013;33(8):4715-4724. Materials Science & Engineering C-Materials for Biological Applications can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands (see also Bacterial Infections).
Our news correspondents report that additional information may be obtained by contacting S. Saidin, Laval University, Univ Hosp Res Center, Quebec City, PQ G1V 0A6, Canada. Additional authors for this research include P. Chevallier, M.R.A. Kadir, H. Hermawan and D. Mantovani.
Keywords for this news article include: Canada, Phosphates, Quebec City, Nanoparticle, Nanotechnology, Hydroxyapatites, Phosphoric Acids, Emerging Technologies, North and Central America, Bacterial Infections and Mycoses
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