By a News Reporter-Staff News Editor at Health & Medicine Week -- New research on Health and Medicine is the subject of a report. According to news reporting originating in Needham, Massachusetts, by NewsRx journalists, research stated, "To report experience in the treatment of persistent corneal epithelial defect using overnight wear of a prosthetic device for the ocular surface. Retrospective interventional case series."
The news reporters obtained a quote from the research, "A clinical database of patients who underwent prosthetic replacement of the ocular surface ecosystem (PROSE) treatment from March 2003 to August 2008 was searched to identify patients treated for persistent corneal epithelial defect. In early 2003, overnight wear of a PROSE device and addition of commercially available, nonpreserved, topical ophthalmic moxifloxacin to the saline in the device reservoir became standard practice at this center when treating persistent corneal epithelial defect. Medical records were abstracted to obtain underlying diagnoses, previous treatments, days to re-epithelialization, and complications for subsequent analysis. PROSE treatment incorporating overnight wear, with adjunctive use of moxifloxacin, was employed in 20 eyes of 19 patients for a total of 372 days. Re-epithelialization occurred in 17 of 20 eyes. Median duration of treatment incorporating overnight wear was 8.5 days (range = 2-76 days). Healing occurred in 14 days in 2 eyes (range = 1-35 days). There were no cases of microbial keratitis. Overnight wear of a PROSE device is effective in promoting healing of Persistent corneal epithelial defect."
According to the news reporters, the research concluded: "In comparison to an earlier series from:: this center, the rate of microbial keratitis as a complication of treatment has been reduced with the use of a nonpreserved topical fourth-generation fluoroquinolone in the device reservoir."
For more information on this research see: Treatment of Persistent Corneal Epithelial Defect With Overnight Wear of a Prosthetic Device for the Ocular Surface. American Journal of Ophthalmology, 2013;156(6):1095-1101. American Journal of Ophthalmology can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; American Journal of Ophthalmology - www.elsevier.com/wps/product/cws_home/601028)
Our news correspondents report that additional information may be obtained by contacting P. Lim, Boston Fdn Sight, Needham, MA 02494, United States. Additional authors for this research include R. Ridges, D.S. Jacobs and P. Rosenthal (see also Health and Medicine).
Keywords for this news article include: Needham, Treatment, Massachusetts, United States, Health and Medicine, North and Central America
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