By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Gram-Positive Bacteria is the subject of a report. According to news originating from Beijing, People's Republic of China, by NewsRx correspondents, research stated, "Probiotics are supplemented to animal diet to support a well-balanced gut microbiota, finally contributing to improved health. The molecular mechanism of probiotics in animal intestine improvement is yet unclear."
Our news journalists obtained a quote from the research from Feed Research Institute, "We investigated the production parameters, gut morphology and microbiota, and mucosal proteome of Arbor Acres broilers (Gallus gallus) supplemented with Enterococcus faecium by performing denaturing gradient gel electrophoresis, quantitative real-time PCR, two-dimensional fluorescence difference gel electrophoresis, and mass spectrometry. E. faecium supplementation promoted the development of immune organs and gut microvilli and enlarged the gut microbial diversity and population. However, it had no effects on daily weight gain and feed intake, and slightly enhanced feed conversion ratio. A total of 42 intestinal mucosal proteins were found to be differentially abundant. Four of them are related to intestinal structure and may extend the absorptive surface area. Of 17 differential proteins related to immune and antioxidant systems, only six are abundant in the broilers fed E. faecium, indicating that these chickens employ less nutrients and energy to deal with immune and antioxidant stresses. These findings have important implications for understanding the probiotic mechanisms of E. faecium on broiler intestine. Probiotic supplementation to animal diet is closely related with improved health. The objective of this study is to determine the molecular mechanisms of probiotic E. faecium achieving its biological mission in the gut of Arbor Acres broilers (G. gallus). E. faecium supplementation did not improve daily weight gain and feed intake; however, it had effects on immune organ and gut microvillus development, and gut microbial diversity and population. Quantitative proteomic analysis of the intestinal mucosa of broilers treated with E. faecium identified 42 intestinal mucosal proteins related to substance metabolism, immune and antioxidant systems, and cell structure."
According to the news editors, the research concluded: "This study identified the E. faecium derived probiotic mechanism on the proteome level."
For more information on this research see: Proteome changes in the intestinal mucosa of broiler (Gallus gallus) activated by probiotic Enterococcus faecium. Journal of Proteomics, 2013;91():226-41. (Elsevier - www.elsevier.com; Journal of Proteomics - www.elsevier.com/wps/product/cws_home/713351)
The news correspondents report that additional information may be obtained from J. Luo, Key Laboratory of Feed Biotechnology of Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, People's Taiwan. Additional authors for this research include A. Zheng, K. Meng, W. Chang, Y. Bai, K. Li, H. Cai, G. Liu and B. Yao (see also Gram-Positive Bacteria).
Keywords for this news article include: Asia, Antioxidants, Beijing, Peptides, Proteins, Proteome, Amino Acids, Enterococcaceae, Protective Agents, Enterococcus faecium, Gram Positive Bacteria, Gram-Positive Bacteria, People's Republic of China.
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