By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators discuss new findings in Cysts. According to news reporting originating in Los Angeles, California, by NewsRx journalists, research stated, "The purpose of this study was to evaluate the reliability and accuracy of cone-beam computed tomographic (CBCT) imaging against the histopathologic diagnosis for the differential diagnosis of periapical cysts (cavitated lesions) from (solid) granulomas. Thirty-six periapical lesions were imaged using CBCT scans."
The news reporters obtained a quote from the research from the University of California, "Apicoectomy surgeries were conducted for histopathological examination. Evaluator 1 examined each CBCT scan for the presence of 6 radiologic characteristics of a cyst (ie, location, periphery, shape, internal structure, effects on surrounding structure, and perforation of the cortical plate). Not every cyst showed all radiologic features (eg, not all cysts perforate the cortical plate). For the purpose of finding the minimum number of diagnostic criteria present in a scan to diagnose a lesion as a cyst, we conducted 6 receiver operating characteristic curve analyses comparing CBCT diagnoses with the histopathologic diagnosis. Two other independent evaluators examined the CBCT lesions. Statistical tests were conducted to examine the accuracy, inter-rater reliability, and intrarater reliability of CBCT images. Findings showed that a score of >= 4 positive findings was the optimal scoring system. The accuracies of differential diagnoses of 3 evaluators were moderate (area under the curve = 0.76, 0.70, and 0.69 for evaluators 1, 2, and 3, respectively). The inter-rater agreement of the 3 evaluators was excellent (alpha = 0.87). The intrarater agreement was good to excellent (kappa = 0.71, 0.76, and 0.77)."
According to the news reporters, the research concluded: "CBCT images can provide a moderately accurate diagnosis between cysts and granulomas."
For more information on this research see: Evaluation of the Reliability and Accuracy of Using Cone-beam Computed Tomography for Diagnosing Periapical Cysts from Granulomas. Journal of Endodontics, 2013;39(12):1485-1490. Journal of Endodontics can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; Journal of Endodontics - www.elsevier.com/wps/product/cws_home/707230)
Our news correspondents report that additional information may be obtained by contacting J. Guo, University of California, Ostrow Sch Dental, Los Angeles, CA 90089, United States. Additional authors for this research include J.H. Simon, P. Sedghizadeh, O.N. Soliman, T. Chapman and R. Enciso (see also Cysts).
Keywords for this news article include: Cysts, California, Los Angeles, United States, Imaging Technology, Computed Tomography, North and Central America
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