By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Gram-Positive Bacteria. According to news reporting from Cairo, Egypt, by NewsRx journalists, research stated, "Cellulose acetate nanofiber mats containing tetracycline hydrochloride were prepared by electrospinning. Incorporation of tetracycline hydrochloride (20wt% based on the weight of cellulose acetate) in the cellulose acetate solution (17% wt/vol in 2:1vol/vol ethanol-dimethyl sulfoxide) did not affect the morphology of the obtained fibers, as tetracycline hydrochloride-loaded cellulose acetate fibers were smooth."
The news correspondents obtained a quote from the research from National Research Center, "The average diameters of these fibers ranged between 50 and 90nm. Determination of the release characteristics of tetracycline hydrochloride from the cellulose acetate nanofiber mats was carried out by total immersion in phosphate buffer solution, that is, in the total immersion method, the maximum amounts of the tetracycline hydrochloride released from the cellulose acetate nanofiber into the medium were 10 and 25%mu g/100ml. Antibacterial activity of prepared tetracycline hydrochloride-loaded as-spun cellulose acetate fiber mate was achieved using Escherichia coli and Staphylococcus aureus as a representative each of Gram-negative and Gram-positive bacteria, respectively."
According to the news reporters, the research concluded: "Antibacterial activity of tetracycline hydrochloride-loaded as-spun cellulose acetate fiber mat showed effectiveness with 77-88% bacteria reduction after 10min-1h for Escherichia coli and approximately 83-85% reduction after 10min-1h for Staphylococcus aureus."
For more information on this research see: Synthesis and characterization of novel drug delivery system based on cellulose acetate electrospun nanofiber mats. Journal of Industrial Textiles, 2014;43(3):319-329. Journal of Industrial Textiles can be contacted at: Sage Publications Inc, 2455 Teller Rd, Thousand Oaks, CA 91320, USA. (Sage Publications - www.sagepub.com/; Journal of Industrial Textiles - jit.sagepub.com)
Our news journalists report that additional information may be obtained by contacting M. Gouda, Natl Res Center, Text Res Div, Cairo, Egypt. Additional authors for this research include A.A. Hebeish and A.I. Aljafari (see also Gram-Positive Bacteria).
Keywords for this news article include: Cairo, Egypt, Africa, Hydrocarbons, Naphthacenes, Tetracyclines, Gram-Positive Bacteria
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