By a News Reporter-Staff News Editor at Biotech Week -- Researchers detail new data in Oncology. According to news reporting originating in Tamil Nadu, India, by NewsRx journalists, research stated, "The application of polymeric materials for therapeutic application is growing exceptionally. In particular, the use of polymeric nanofibers has found a wide range of applications in diverse biomedical fields, such as tissue engineering, implantation of medicinal devices and artificial organs, prostheses, ophthalmology, dentistry, bone repair, and many other medical fields."
The news reporters obtained a quote from the research from Anna University, "This study will focus on the fabrication of polysulphone/nanohydroxyapatite (PSu/nHA) composite nanofibers by using electro spinning techniques that contain varying concentrations of HA 0-8%. The prepared nanofiber mats were characterized using FTIR, SEM and XRD. The bioactivity and drug release kinetics of the samples after loading with 5-FU drug were analyzed. Further, their effects on cancer cells were analyzed using MTT assay. The in vitro drug release showed a prolonged pattern of release thereby allowing the spread of the drugs inside the target site wherever the tumor may exist. The results from the MTT assay showed that the metabolized activities of the cancerous cells were greatly affected with negligible effect of normal cells."
According to the news reporters, the research concluded: "The results from the study showed that the prepared composite could potentially be used in the management of gastric cancer post-surgery."
For more information on this research see: Fabrication of polysulphone/hydroxyapatite nanofiber composite implant and evaluation of their in vitro bioactivity and biocompatibility towards the post-surgical therapy of gastric cancer. Chemical Engineering Journal, 2013;234():380-388. Chemical Engineering Journal can be contacted at: Elsevier Science Sa, PO Box 564, 1001 Lausanne, Switzerland. (Elsevier - www.elsevier.com; Chemical Engineering Journal - www.elsevier.com/wps/product/cws_home/601273)
Our news correspondents report that additional information may be obtained by contacting S.S. Saravanabhavan, Anna University, Dept. of Chem, Madras 620025, Tamil Nadu, India (see also Oncology).
Keywords for this news article include: Asia, Tissue Engineering, Biomedical Engineering, Biomedicine, India, Surgery, Therapy, Oncology, Nanofiber, Tamil Nadu, Bioengineering, Gastric Cancer, Nanotechnology, Medical Devices, Gastroenterology, Emerging Technologies
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