By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on Environmental Science are presented in a new report. According to news reporting originating in Guangzhou, People's Republic of China, by NewsRx journalists, research stated, "Bisphenol A (BPA) is a ubiquitous environmental contaminant in food products and aquatic ecosystems. Its endocrine and developmental toxicity presents a serious concern to human health and an effective high-throughput method for its detection is desirable."
The news reporters obtained a quote from the research from the Guangdong University of Technology, "In this paper, water-soluble quantum dots (QDs) have been conjugated covalently with BPA antibodies and the conjugate has been utilized in a competitive fluorescence-linked immunoassay (FLISA). Cd-doped ZnO QDs were functionalized with poly(amidoamine) (PAMAM) dendrimers, as evidenced by ultraviolet absorption spectrum and fluorescence emission spectra analyses, and this led to their successful transfer into aqueous solution. Biological mass spectrometry demonstrated that the bisphenol A antibodies were successfully coupled to the water-soluble QDs, and the structures of these conjugates kept intact. The FLISA method allowed for BPA determination in a linear working range of 20.8-330.3 ng mL(-1) with the limit of detection (LOD) of 13.1 ng mL(-1). The recoveries of BPA from water samples were from 85.92% to 109.62%."
According to the news reporters, the research concluded: "A rapid and sensitive FLISA was developed by utilizing novel QD coupling method and validated for use in aqueous samples."
For more information on this research see: Cd-doped ZnO quantum dots-based immunoassay for the quantitative determination of bisphenol A. Chemosphere, 2014;95():105-10. (Elsevier - www.elsevier.com; Chemosphere - www.elsevier.com/wps/product/cws_home/362)
Our news correspondents report that additional information may be obtained by contacting J. Zhang, Dept. of Pharmaceutical Engineering, Faculty of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, People's Taiwan. Additional authors for this research include S.Q. Zhao, K. Zhang and J.Q Zhou (see also Environmental Science).
Keywords for this news article include: Asia, Antibodies, Guangzhou, Immunology, Quantum Dots, Blood Proteins, Immunoglobulins, Quantum Physics, Environmental Science, People's Republic of China.
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