Our news journalists obtained a quote from the research, "However, the microscopic understanding of how and when the nanowires penetrate cell membranes is still lacking, and the degree to which actual membrane penetration occurs is controversial. Here we present results from a mechanical continuum model of elastic cell membrane penetration through two mechanisms, namely through 'impaling' as cells land onto a bed of nanowires, and through 'adhesion-mediated' penetration, which occurs as cells spread on the substrate and generate adhesion force. Our results reveal that penetration is much more effective through the adhesion mechanism, with NW geometry and cell stiffness being critically important. Stiffer cells have higher penetration efficiency, but are more sensitive to NW geometry."
According to the news editors, the research concluded: "These results provide a guide to designing nanowires for applications in cell membrane penetration."
For more information on this research see: Mechanical Model of Vertical Nanowire Cell Penetration.
Our news journalists report that additional information may be obtained by contacting X. Xie,
Keywords for this news article include: Nanowire,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
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