The patent's inventors are Ding, Jiang (
This patent was filed on
From the background information supplied by the inventors, news correspondents obtained the following quote: "Cardiac rhythm management devices are implantable devices that provide electrical stimulation to selected chambers of the heart in order to treat disorders of cardiac rhythm. A pacemaker, for example, is a cardiac rhythm management device that paces the heart with timed pacing pulses. The most common condition for which pacemakers are used is in the treatment of bradycardia, where the ventricular rate is too slow. Atrio-ventricular conduction defects (i.e., AV block) that are permanent or intermittent and sick sinus syndrome represent the most common causes of bradycardia for which permanent pacing may be indicated. If functioning properly, the pacemaker makes up for the heart's inability to pace itself at an appropriate rhythm in order to meet metabolic demand by enforcing a minimum heart rate and/or artificially restoring AV conduction.
"Pacing therapy can also be used in the treatment of heart failure, which refers to a clinical syndrome in which an abnormality of cardiac function causes a below normal cardiac output that can fall below a level adequate to meet the metabolic demand of peripheral tissues. When uncompensated, it usually presents as congestive heart failure due to the accompanying venous and pulmonary congestion. Heart failure can be due to a variety of etiologies with ischemic heart disease being the most common. It has been shown that some heart failure patients suffer from intraventricular and/or interventricular conduction defects (e.g., bundle branch blocks) such that their cardiac outputs can be increased by improving the synchronization of ventricular contractions with electrical stimulation. In order to treat these problems, implantable cardiac devices have been developed that provide appropriately timed electrical stimulation to one or more heart chambers in an attempt to improve the coordination of atrial and/or ventricular contractions, termed cardiac resynchronization therapy (CRT). Ventricular resynchronization is useful in treating heart failure because, although not directly inotropic, resynchronization can result in a more coordinated contraction of the ventricles with improved pumping efficiency and increased cardiac output. Currently, a most common form of CRT applies stimulation pulses to both ventricles, either simultaneously or separated by a specified biventricular offset interval, and after a specified atrio-ventricular delay interval with respect to the detection of an intrinsic atrial contraction and/or an atrial pace. Appropriate specification of these pacing parameters is necessary in order to achieve optimum improvement in cardiac function, and it is this problem with which the present invention is primarily concerned."
Supplementing the background information on this patent, NewsRx reporters also obtained the inventors' summary information for this patent: "A pacing system computes optimal cardiac resynchronization pacing parameters using intrinsic conduction intervals. In various embodiments, values for atrio-ventricular delay intervals are each computed as a function of an intrinsic atrio-ventricular interval and a parameter reflective of an interventricular conduction delay. Examples of the parameter reflective of the interventricular conduction delay include QRS width and interval between right and left ventricular senses.
"In one embodiment, a pacing system includes sensing/pacing channels and a controller. The sensing/pacing channels sense cardiac electrical activity and deliver pacing pulses. The controller determines an atrio-ventricular delay (AVD) interval using at least an intrinsic atrio-ventricular interval measured following an atrial pace and a parameter reflective of an interventricular conduction delay. Using the first AVD interval, the controller controls the delivery of the pacing pulses in accordance with an AV sequential pacing mode.
"In one embodiment, a pacing system includes means for determining at least two AVD intervals and an implantable device that delivers a cardiac resynchronization therapy using the two AVD intervals. One of the AVD intervals is for use in an atrio-ventricular sequential pacing mode and is determined using an intrinsic atrio-ventricular interval measured between an atrial pace and a ventricular sense and a parameter reflective of an interventricular conduction delay. The other AVD interval is for use in an atrial tracking mode and is determined using an intrinsic atrio-ventricular interval measured between an atrial sense and another ventricular sense and the parameter reflective of the interventricular conduction delay.
"In one embodiment, a method for cardiac pacing is provided. An intrinsic atrio-ventricular interval is measured between an atrial pace and a ventricular sense. An AVD interval is determined using the first intrinsic atrio-ventricular interval and a parameter reflective of an interventricular conduction delay. The AVD interval is used to control delivery of pacing pulses in accordance with an AV sequential pacing mode.
"In one embodiment, a method for cardiac pacing is provided. Two intrinsic atrio-ventricular intervals, one following an atrial pace and the other following an atrial sense, are measured. A parameter reflective of an interventricular conduction delay is measured. An AVD interval is used for pacing in an atrio-ventricular sequential pacing mode, and its value is computed using the intrinsic atrio-ventricular interval following the atrial pace, the parameter reflective of the interventricular conduction delay, and predetermined coefficients. Another AVD interval is used for pacing in an atrial tracking pacing mode, and its value is computed using the intrinsic atrio-ventricular interval following the atrial sense, the parameter reflective of the interventricular conduction delay, and predetermined coefficients.
"This Summary is an overview of some of the teachings of the present application and not intended to be an exclusive or exhaustive treatment of the present subject matter. Further details about the present subject matter are found in the detailed description and appended claims. Other aspects of the invention will be apparent to persons skilled in the art upon reading and understanding the following detailed description and viewing the drawings that form a part thereof. The scope of the present invention is defined by the appended claims and their legal equivalents."
For the URL and additional information on this patent, see: Ding, Jiang; Yu, Yinghong;
Keywords for this news article include: Therapy, Treatment, Cardiology, Heart Disease, Heart Failure, Pacing System, Medical Devices,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
Most Popular Stories
- Obama Administration Releases Proposal to Regulate For-Profit Colleges
- Koch Brothers Step up Anti-Obamacare Campaign
- Elizabeth Vargas' Husband Marc Cohn Addresses Rumors
- Keurig Adds Peet's coffee, Alters Starbucks deal
- Quiznos Files for Chapter 11
- U.S. to Relinquish Gov't Control Over Internet
- SoCalGas Reaches Record Spend on Diversity Suppliers
- Vybz Kartel Convicted of Murder
- FDIC Sues Big Banks Over Rate Manipulation
- U.S. Consumer Sentiment Falls in Early March