By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Methionine. According to news reporting originating in Wuhan, People's Republic of China, by NewsRx journalists, research stated, "We report the selective recovery of S-adenosylmethionine (SAM) from fermentation broths using a two-stage supported liquid membrane system with strip dispersion (SLM-SD). The system utilized two MiniModule ® hollow-fiber membrane modules as microporous supports and an organic membrane solution consisting of the extractants of sodium di-2-ethylhexyl sulfosuccinate (AOT), di-(2-ethylhexyl)phosphoric acid (DEHPA), and trioctylphosphine oxide (TOPO) in the solvent n-octanol."
The news reporters obtained a quote from the research from the Huazhong University of Science and Technology, "SAM was extracted in the first membrane module. Methionine (Met) was captured by the first stripping solution and further purified in the second membrane module. pH values in the feed phase and the first and second stripping solutions, extractant concentrations, NaCl concentration, and the SAM acceptor in the first stripping solution were optimized. Strip dispersion mixing speed, pressure differences across the membranes, and flow rates of the feed and strip dispersion phases were investigated experimentally. The optimal extractant concentrations were: AOT 2.78 wt%, DEHPA 27.0 wt%, and TOPO 1.61 wt%. The optimal pH values in the feed phase and the first and second stripping solution were 3.0, 2.5, and 1.0, respectively."
According to the news reporters, the research concluded: "SAM extraction efficiency of 98.7%, SAM recovery efficiency of 91.8% and Met removal efficiency of 85.4% were achieved within 5 h. Finally, the mass transfer analysis indicated that the mass transfer resistances from the extraction reaction and the membrane phase were predominant."
For more information on this research see: Two-stage recovery of S-adenosylmethionine using supported liquid membranes with strip dispersion. Process Biochemistry, 2013;48(12):1980-1991. Process Biochemistry can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Process Biochemistry - www.elsevier.com/wps/product/cws_home/422857)
Our news correspondents report that additional information may be obtained by contacting Y.X. Tang, Huazhong University of Science & Technology, Natl Engn Res Center Nanomed, Wuhan 430074, People's Republic of China. Additional authors for this research include W. Liu, J.L. Wan, Y.X. Wang and X.L. Yang (see also Methionine).
Keywords for this news article include: Asia, Wuhan, S-Adenosylmethionine, People's Republic of China
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