By a News Reporter-Staff News Editor at Journal of Technology -- Research findings on Raman Spectroscopy are discussed in a new report. According to news reporting originating in Hsinchu, Taiwan, by VerticalNews journalists, research stated, "The use of Au@SiO2 core/shell nanoparticle (NP) assemblage with highly sensitive surface-enhanced Raman scattering (SERS) was investigated for the determination of glucose and uric acid in this study. Rhodamine 6G dye molecules were used to evaluate the SERS enhancement factor for the synthesized Au@SiO2 core/shell NPs with various silica shell thicknesses."
The news reporters obtained a quote from the research from National Synchrotron Radiation Research Center, "The enhancement of SERS signal from Rhodamine 6G was found to increase with a decrease in the shell thickness. The core/shell assemblage with silica layer of 1-2nm over a Au NP of 36nm showed the highest SERS signal. Our results show that the SERS technique is able to detect glucose and uric acid within wide concentration ranges, i.e. 20ng/dL to 20mg/dL (10(-12)-10(-3)M) and 16.8ng/dL to 2.9mg/dL (10(-11)-1.72x10(-4)M), respectively, with associated lower detection limits of 20ng/dL (1.0x10(-12)M) and 16.8ng/dL (1.0x10(-11)M)."
According to the news reporters, the research concluded: "Our work offers a low-cost route to the fabrication of agile sensing devices applicable to the monitoring of disease progression."
For more information on this research see: Au@SiO2 core/shell nanoparticle assemblage used for highly sensitive SERS-based determination of glucose and uric acid. Journal of Raman Spectroscopy, 2013;44(12):1671-1677. Journal of Raman Spectroscopy can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Journal of Raman Spectroscopy - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1097-4555)
Our news correspondents report that additional information may be obtained by contacting T.T.B. Quyen, Natl Synchrotron Radiat Res Center, Hsinchu 30076, Taiwan. Additional authors for this research include W.N. Su, K.J. Chen, C.J. Pan, J. Rick, C.C. Chang and B.J. Hwang.
Keywords for this news article include: Asia, Taiwan, Hsinchu, Raman Spectroscopy
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