By a News Reporter-Staff News Editor at Science Letter -- Current study results on Keto Acids have been published. According to news reporting originating in Shanghai, People's Republic of China, by NewsRx journalists, research stated, "Pt/MIL-101 catalyst was prepared via a facile impregnation method and was tested for the chiral hydrogenation of alpha-ketoesters after chirally modified with cinchona alkaloid. The powder XRD, N-2 adsorption-desorption, TEM, and CO chemisorption were employed to characterize the Pt/MIL-101 catalyst."
The news reporters obtained a quote from the research from East China Normal University, "The Pt/MIL-101 catalyst was proved effective for the asymmetric hydrogenation of ethyl pyruvate and ethyl 2-oxo-4-phenylbutyrate after chirally modified with cinchonidine. Up to 4469 h(-1) TOF with 76.5% ee of ®-(+)-ethyl lactate was obtained with the cinchonidine-modified Pt/MIL-101 catalyst in acetic acid. The fastest chiral hydrogenation of ethyl pyruvate with the cinchonidine-modified Pt/MIL-101 catalyst took place in neat water with medium enantioselectivity. While for the chiral hydrogenation of ethyl 2-oxo-4-phenylbutyrate with the cinchonidine-modified Pt/MIL-101 catalyst, over 2000 h(-1) TOF with 76.8% ee value was achieved in a mixed solvent containing acetic acid and ethanol with an equal volume. Of particular note is that the Pt/MIl-101 catalyst could be reused at least four times without distinct loss in activity or enantioselectivity with addition of fresh chiral modifier each time in the chiral hydrogenation of ethyl pyruvate."
According to the news reporters, the research concluded: "The catalytic performance of Pt/MIL-101 catalyst was also compared for the chiral hydrogenation of ethyl pyruvate with the commercial Pt/C and Pt/Al2O3 catalysts after modification with cinchona alkaloid."
For more information on this research see: Pt nanoparticles entrapped in mesoporous metal-organic frameworks MIL-101 as an efficient and recyclable catalyst for the asymmetric hydrogenation of alpha-ketoesters. Journal of Molecular Catalysis A-Chemical, 2013;377():108-114. Journal of Molecular Catalysis A-Chemical can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands (see also Keto Acids).
Our news correspondents report that additional information may be obtained by contacting H.Y. Pan, E China Normal Univ, Shanghai Key Lab Green Chem & Chem Proc, Dept. of Chem, Shanghai 200062, People's Republic of China. Additional authors for this research include X.H. Li, D.M. Zhang, Y.J. Guan and P. Wu.
Keywords for this news article include: Asia, Shanghai, Pyruvates, Keto Acids, Nanoparticle, Nanotechnology, Emerging Technologies, People's Republic of China
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