By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators publish new report on Nuclear Magnetic Resonance. According to news reporting originating in Nottingham, United Kingdom, by NewsRx journalists, research stated, "Nuclear magnetic resonance (NMR) techniques are extensively used in many areas of basic and clinical research, as well as in diagnostic medicine. However, NMR signals are intrinsically weak, and this imposes substantial constraints on the amounts and concentrations of materials that can be detected."
The news reporters obtained a quote from the research from the University of Nottingham, "The signals are weak because of the low energies characteristic of NMR and the resulting very low (typically 0.0001-0.01%) polarization of the nuclear spins. Here, we show that exposure to very low temperatures and high magnetic fields, in conjunction with nanoparticle-mediated relaxation enhancement, can be used to generate extremely high nuclear polarization levels on a realistic timescale; with copper nanoparticles at 15 mK and 14 T, (13)C polarization grew towards its equilibrium level of 23% with an estimated half-time of about 60 hours. This contrasts with a (13)C half-time of at least one year in the presence of aluminium nanoparticles. Cupric oxide nanoparticles were also effective relaxation agents. Our findings lead us to suspect that the relaxation may be mediated, at least in part, by the remarkable magnetic properties that some nanoparticle preparations can display."
According to the news reporters, the research concluded: "This methodology offers prospects for achieving polarization levels of 10-50% or more for many nuclear species, with a wide range of potential applications in structural biology and medicine."
For more information on this research see: High polarization of nuclear spins mediated by nanoparticles at millikelvin temperatures. Physical Chemistry Chemical Physics, 2013;15(25):10413-7. (Royal Society of Chemistry - www.rsc.org/; Physical Chemistry Chemical Physics - pubs.rsc.org/en/journals/journalissues/cp)
Our news correspondents report that additional information may be obtained by contacting J.R. Owers-Bradley, School of Physics and Astronomy, University of Nottingham, Nottingham, UK. Additional authors for this research include A.J. Horsewill, D.T. Peat, K.S. Goh and D.G Gadian (see also Nuclear Magnetic Resonance).
Keywords for this news article include: Europe, Nottingham, Nanoparticle, United Kingdom, Nanotechnology, Emerging Technologies, Nuclear Magnetic Resonance.
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