By a News Reporter-Staff News Editor at Biotech Week -- New research on Biomedicine and Biomedical Engineering is the subject of a report. According to news reporting originating from Cambridge, United Kingdom, by NewsRx correspondents, research stated, "Polymeric fibrous scaffolds have been considered as replacements for load-bearing soft tissues, because of their ability to mimic the microstructure of natural tissues. Poor toughness of fibrous materials results in failure, which is an issue of importance to both engineering and medical practice."
Our news editors obtained a quote from the research from the University of Cambridge, "The toughness of fibrous materials depends on the ability of the microstructure to develop toughening mechanisms. However, such toughening mechanisms are still not well understood, because the detailed evolution at the microscopic level is difficult to visualize. A novel and simple method was developed, namely, a sample-taping technique, to examine the detailed failure mechanisms of fibrous microstructures. This technique was compared with in situ fracture testing by scanning electron microscopy. Examination of three types of fibrous networks showed that two different failure modes occurred in fibrous scaffolds. For brittle cracking in gelatin electrospun scaffolds, the random network morphology around the crack tip remained during crack propagation. For ductile failure in polycaprolactone electrospun scaffolds and nonwoven fabrics, the random network deformed via fiber rearrangement, and a large number of fiber bundles formed across the region in front of the notch tip. These fiber bundles not only accommodated mechanical strain, but also resisted crack propagation and thus toughened the fibrous scaffolds."
According to the news editors, the research concluded: "Such understanding provides insight for the production of fibrous materials with enhanced toughness."
For more information on this research see: Failure mechanisms in fibrous scaffolds. Acta Biomaterialia, 2013;9(7):7326-34. (Elsevier - www.elsevier.com; Acta Biomaterialia - www.elsevier.com/wps/product/cws_home/702994)
The news editors report that additional information may be obtained by contacting C.T. Koh, Cambridge University Engineering Department, Trumpington Street, Cambridge CB2 1PZ, UK. Additional authors for this research include D.G. Strange, K. Tonsomboon and M.L Oyen (see also Biomedicine and Biomedical Engineering).
Keywords for this news article include: Tissue Engineering, Biomedicine and Biomedical Engineering, Europe, Cambridge, United Kingdom, Bioengineering.
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