By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Nanoparticles. According to news reporting originating from Cleveland, Ohio, by NewsRx correspondents, research stated, "Nanoparticles (NPs), due to their size-dependent physical and chemical properties, have shown remarkable potential for a wide range of applications over the past decades. Particularly, the biological compatibilities and functions of NPs have been extensively studied for expanding their potential in areas of biomedical application such as bioimaging, biosensing, and drug delivery."
Our news editors obtained a quote from the research from Cleveland State University, "In doing so, surface functionalization of NPs by introducing synthetic ligands and/or natural biomolecules has become a critical component in regard to the overall performance of the NP system for its intended use. Among known examples of surface functionalization, the construction of an artificial cell membrane structure, based on phospholipids, has proven effective in enhancing biocompatibility and has become a viable alternative to more traditional modifications, such as direct polymer conjugation. Furthermore, certain bioactive molecules can be immobilized onto the surface of phospholipid platforms to generate displays more reminiscent of cellular surface components. Thus, NPs with membrane-mimetic displays have found use in a range of bioimaging, biosensing, and drug delivery applications."
According to the news editors, the research concluded: "This review herein describes recent advances in the preparations and characterization of integrated functional NPs covered by artificial cell membrane structures and their use in various biomedical applications."
For more information on this research see: Membrane mimetic surface functionalization of nanoparticles: Methods and applications. Advances in Colloid and Interface Science, 2013;197():68-84. Advances in Colloid and Interface Science can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Advances in Colloid and Interface Science - www.elsevier.com/wps/product/cws_home/500842)
The news editors report that additional information may be obtained by contacting J. Weingart, Cleveland State University, Cleveland, OH 44115, United States. Additional authors for this research include P. Vabbilisetty and X.L. Sun (see also Nanoparticles).
Keywords for this news article include: Ohio, Therapy, Cleveland, United States, Nanotechnology, Drug Delivery Systems, Emerging Technologies, North and Central America
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