By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Nanoparticles. According to news reporting out of Tokyo, Japan, by NewsRx editors, research stated, "Highly porous nanocellulose aerogels prepared by freeze-drying from Various nanofibrillar cellulose (NFC) hydrogels are introduced as nanoparticle reservoirs for oral drug delivery systems. Here we show that beclomethasone dipropionate (BDP) nanoparticles coated with amphiphilic hydrophobin proteins can be well integrated into the NFC aerogels."
Our news journalists obtained a quote from the research from the University of Tokyo, "NFCs from four different origins are introduced and compared to microcrystalline cellulose (MCC). The nanocellulose aerogel scaffolds made from red pepper (RC) and MCC release the drug immediately, while bacterial cellulose (BC), quince seed (QC) and TEMPO-oxidized birch cellulose-based (TC) aerogels show sustained drug release. Since the release of the drug is controlled by the structure and interactions between the nanoparticles and the cellulose matrix, modulation of the matrix formers enable a control of the drug release rate."
According to the news editors, the research concluded: "These nanocomposite structures can be very useful in many pharmaceutical nanoparticle applications and open up new possibilities as carriers for controlled drug delivery."
For more information on this research see: Drug release from nanoparticles embedded in four different nanofibrillar cellulose aerogels. European Journal of Pharmaceutical Sciences, 2013;50(1):69-77. European Journal of Pharmaceutical Sciences can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; European Journal of Pharmaceutical Sciences - www.elsevier.com/wps/product/cws_home/523997)
Our news journalists report that additional information may be obtained by contacting H. Valo, University of Tokyo, Grad Sch Agr, Dept. of Biomat Sci, Tokyo 1138654, Japan. Additional authors for this research include S. Arola, P. Laaksonen, M. Torkkeli, L. Peltonen, M.B. Linder, R. Serimaa, S. Kuga, J. Hirvonen and T. Laaksonen (see also Nanoparticles).
Keywords for this news article include: Asia, Tokyo, Japan, Therapy, Nanotechnology, Drug Delivery Systems, Emerging Technologies
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