By a News Reporter-Staff News Editor at Heart Disease Weekly -- Researchers detail new data in Heart Diseases and Conditions. According to news reporting out of Chiba, Japan, by NewsRx editors, research stated, "To investigate safety and feasibility of imaging unprotected left main (ULM) using frequency-domain optical coherence tomography (FD-OCT) compared with intravascular ultrasound (IVUS). IVUS has been used to assess and guide percutaneous coronary intervention (PCI) of ULM disease."
Our news journalists obtained a quote from the research from the Department of Cardiology, "FD-OCT offers 10-fold higher axial resolution than IVUS and its high-speed image acquisition obviates the need for proximal balloon occlusion. We prospectively enrolled 35 consecutive patients with ULM disease. FD-OCT and IVUS assessments were attempted pre- and post-PCI and compared in regards to safety, ability to image the region of interest (ROI), number of pullbacks, volume of contrast and ability to detect malapposition, dissection, and thrombus. Patients were followed for 1 year when FD-OCT imaging was repeated. FD-OCT required more repeated pullbacks to image the ROI compared to IVUS. Mean lumen and stent areas were similar between FD-OCT and IVUS (11.24 +/- 2.66 vs. 10.85 +/- 2.47 mm(2), P=0.13 and 10.44 +/- 2.33 vs. 10.49 +/- 2.32 mm(2), P=0.82, respectively), whereas imaged stent length was shorter with FD-OCT. Malapposition areas and volumes were larger and more edge dissections were detected by FD-OCT. There were no clinical adverse events and no complications associated with FD-OCT at baseline and 1-year follow-up. All dissections were healed, whereas stent malapposition was still detected at follow-up. FD-OCT assessment of ULM is feasible and safe."
According to the news editors, the research concluded: "Direct comparisons with IVUS reveal that FD-OCT achieved imaging completeness less often, whereas it was more sensitive in detecting malapposition and edge dissections, and similar to IVUS in the assessment of lumen and stent dimensions."
For more information on this research see: Frequency-domain optical coherence tomography assessment of unprotected left main coronary artery disease-A comparison with intravascular ultrasound. Catheterization and Cardiovascular Interventions, 2013;82(3):E173-E183. Catheterization and Cardiovascular Interventions can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Catheterization and Cardiovascular Interventions - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1522-726X)
Our news journalists report that additional information may be obtained by contacting Y. Fujino, New Tokyo Hosp, Dept. of Cardiol, Chiba, Japan. Additional authors for this research include H.G. Bezerra, G.F. Attizzani, W. Wang, H. Yamamoto, D. Chamie, T. Kanaya, E. Mehanna, S. Tahara, S. Nakamura and M.A. Costa (see also Heart Diseases and Conditions).
Keywords for this news article include: Asia, Chiba, Japan, Angiology, Cardiology, Intravascular, Coronary Artery, Arteriosclerosis, Imaging Technology, Myocardial Ischemia, Cardiovascular Diseases, Arterial Occlusive Diseases, Optical Coherence Tomography, Heart Diseases and Conditions
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2013, NewsRx LLC