By a News Reporter-Staff News Editor at Biotech Week -- New research on Enzymes and Coenzymes is the subject of a report. According to news originating from Dalian, People's Republic of China, by NewsRx correspondents, research stated, "A novel organically modified mesocellular carbon foam (OMCF) was synthesized to enhance the bioactivity of acetylcholinesterase (AChE) and integrated with gold nanoparticles to fabricate amperometric biosensor for ultrasensitive detection of organophosphate pesticide (OP) in drinking water. The OMCF was prepared by functionalizing MCF with o-phenylenediamine through a post-synthesis procedure."
Our news journalists obtained a quote from the research from the Dalian University of Technology, "The organically modification process produced plentiful amino group on the mesowall, resulting in a benign microenvironment inside the MCF. Further N-2 sorption isotherms and IR spectra studies indicated the OMCF had well distributed mesopores and functional groups on the mesowalls. AChE was entrapped in the mesopores of OMCF via physical adsorption, and the bioactivity of the enzyme encapsulated in OMCF was measured to be 1.33 times higher than that in solution by UV-vis spectrometer. Electrochemical impedance spectra studies indicated the introduction of gold nanoparticles could further improve the conductivity of the solid matrix."
According to the news editors, the research concluded: "Based on the inhibition action of OP on AChE, the OMCF based AChE electrochemical biosensor showed a wide linear range (0.05 ppb to 5 ppb) toward monocrotophos, a model highly toxic OP, and high accuracy and good reproducibility in drinking water analysis."
For more information on this research see: Post-Synthesis of Organically Grafted Nanoporous Carbon for Acetylcholinesterase Activity Improvement and Organophosphate Pesticide Detection. Science of Advanced Materials, 2013;5(8):1097-1104. Science of Advanced Materials can be contacted at: Amer Scientific Publishers, 26650 The Old Rd, Ste 208, Valencia, CA 91381-0751, USA. (American Scientific Publishers - www.aspbs.com/)
The news correspondents report that additional information may be obtained from F.F. Huang, Dalian University of Technology, Sch Chem, Dalian 116023, People's Republic of China. Additional authors for this research include J.M. Wang, S. Wu, Y.F. Zhang and T. Yang (see also Enzymes and Coenzymes).
Keywords for this news article include: Asia, Dalian, Chemistry, Biosensing, Hydrolases, Pesticides, Agrochemicals, Bioengineering, Electrochemical, Bionanotechnology, Nanobiotechnology, Gold Nanoparticles, Acetylcholinesterase, Emerging Technologies, Enzymes and Coenzymes, People's Republic of China
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