"We are extremely pleased that the EMA has granted orphan drug status to GMI-1070 for patients with sickle cell disease experiencing VOC," said
GMI-1070, which has previously received both Orphan Drug and Fast Track status for VOC from the
GlycoMimetics is a clinical stage biotechnology company focused on the discovery and development of novel glycomimetic drugs to address unmet medical needs resulting from diseases in which carbohydrate biology plays a key role. Glycomimetics are molecules that mimic the structure of carbohydrates involved in important biological processes. Using its expertise in carbohydrate chemistry and knowledge of carbohydrate biology, the company is developing a pipeline of glycomimetic drug candidates that inhibit disease-related functions of carbohydrates, such as the roles they play in inflammation, cancer and infection. For additional information, please visit the company’s web site at http://www.glycomimetics.com.
About Sickle Cell Disease and VOC
Sickle cell disease is a prevalent genetic disorder worldwide. Due to increasing global migration, the number of sickle cell carriers in European countries is increasing steadily. It is a chronic condition causing substantial illness and death. The main clinical feature of sickle cell disease is periodic painful vaso-occlusive crisis episodes, known as VOC or pain crises, which result in clinical complications, interruptions in patients’ lives, and cumulative irreversible damage that impacts the morbidity and mortality of patients. Treatment for VOC today consists primarily of supportive therapy, in the form of hydration and pain control, typically requiring extended hospitalization.
GMI-1070 is intended to treat VOC by inhibiting the cell activation and enhanced cell adhesion that causes the ischemia and pain. GlycoMimetics selected VOC of sickle cell disease as the first potential indication for GMI-1070.
Most Popular Stories
- Twitter Names Woman to Board
- Aspen Contracting Adding 300 Jobs
- Obamacare Doing Just Fine, Ky. Governor Says
- Rand Paul Signs up for Obamacare
- Hispanic Employment Improves in November
- U.S. Chamber to Run Ads in Idaho, W.Va.
- U.S. Unemployment Rate Dips to 7 Percent
- Consumer Spending Rises, Incomes Fall
- American Eagle Issues Weak Q4 Outlook
- NSA Tracks 5 Billion Cellphone Records a Day