By a News Reporter-Staff News Editor at Science Letter -- Current study results on Nanoparticles have been published. According to news reporting out of Ulm, Germany, by NewsRx editors, research stated, "In this study, time-of-flight secondary ion mass spectrometry (ToF-SIMS) and advanced electron microscopy (scanning electron microscopy (SEM), scanning transmission electron microscopy (STEM) and transmission electron microscopy (TEM)) were applied to detect and analyse different nano-scaled protein coatings on gold nanoparticles (NP). The NP were coated with collagen type I and fibronectin as well as different combinations of these proteins."
Our news journalists obtained a quote from the research from the University of Ulm, "These two main proteins in human cell organization and tissue formation were identified with the aid of ToF-SIMS by typical amino acid mass peak detection. In addition, the protein-coated particles were investigated by TEM and SEM to get information about the protein structure, the protein layer thickness on the particle surfaces and the reaction of NP in different protein solutions. In this study, a differentiation of diverse protein induced particle agglomeration was proven. The investigations of this study were part of the Specific Targeted Research Project CellNanoTox (project no."
According to the news editors, the research concluded: "NMP4-CT-2006-032731) funded by the European Commission under the 6th EU Framework Programme for Research and Technological Development."
For more information on this research see: Detection of protein coatings on nanoparticles surfaces by ToF-SIMS and advanced electron microscopy. Surface and Interface Analysis, 2013;45(9):1340-1346. Surface and Interface Analysis can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - www.wiley.com/; Surface and Interface Analysis - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1096-9918)
Our news journalists report that additional information may be obtained by contacting J. Neunzehn, Univ Ulm, Electron Microscopy Grp Mat Sci, D-89081 Ulm, Germany. Additional authors for this research include F. Draude, U. Golla-Schindler, H.F. Arlinghaus and H.P. Wiesmann (see also Nanoparticles).
Keywords for this news article include: Ulm, Europe, Germany, Nanotechnology, Emerging Technologies
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