By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Nanoparticles have been published. According to news reporting originating in Charlottetown, Canada, by NewsRx journalists, research stated, "Gold nanoparticles can be used as molecular contrast agents binding specifically to cancer sites and thus delineating tumor regions. Imaging gold nanoparticles deeply embedded in tissues with optical techniques possesses significant challenges due to multiple scattering of optical photons that blur the obtained images."
The news reporters obtained a quote from the research from the University of Prince Edward Island, "Both diagnostic and therapeutic applications can benefit from a minimally invasive technique that can identify, localize, and quantify the payloads of gold nanoparticles deeply embedded in biological tissues. An optical radiance technique is applied to map localized inclusions of gold nanorods in 650- to 900-nm spectral range in a porcine phantom that mimics prostate geometry. Optical radiance defines a variation in the angular density of photons impinging on a selected point in the tissue from various directions. The inclusions are formed by immersing a capillary filled with gold nanorods in the phantom at increasing distances from the detecting fiber. The technique allows the isolation of the spectroscopic signatures of the inclusions from the background and identification of inclusion locations in the angular domain. Detection of similar to 4 x 10(10) gold nanoparticles or 0.04 mg Au/mL (detector-inclusion separation 10 mm, source-detector separation 15 mm) in the porcine tissue is demonstrated."
According to the news reporters, the research concluded: "The encouraging results indicate a promising potential of radiance spectroscopy in early prostate cancer diagnostics with gold nanoparticles."
For more information on this research see: Optical detection of gold nanoparticles in a prostate-shaped porcine phantom. Journal of Biomedical Optics, 2013;18(7):319-328. Journal of Biomedical Optics can be contacted at: Spie-Soc Photo-Optical Instrumentation Engineers, 1000 20TH St, PO Box 10, Bellingham, WA 98225, USA (see also Nanoparticles).
Our news correspondents report that additional information may be obtained by contacting S. Grabtchak, University of Prince Edward Island, Atlantic Vet College, Dept. of Biomed Sci, Charlottetown, PE C1A 4P3, Canada. Additional authors for this research include E. Tonkopi and W.M. Whelan.
Keywords for this news article include: Canada, Nanorod, Charlottetown, Nanotechnology, Gold Nanoparticles, Prince Edward Island, Emerging Technologies, North and Central America
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