The news reporters obtained a quote from the research, "The injectable vaccines are commonly produced using transient expression of target gene delivered into genetically unmodified plant host via viral or bacterial vectors. Most viral vectors are based on plant RNA viruses, where nonessential sequences are replaced with the gene of interest. Utilization of viral hybrids that consist of genes and regulatory elements of different virus species, or transcomplementation systems (vector/transgene) had a substantial impact on the level of target protein expression. Development and introduction of agroviral hybrid vectors that combine genetic elements of bacterial binary plasmids and plant viral vectors, and agroinfiltration as a tool of the vector delivery have resulted in significant progress in large-scale production of recombinant vaccines and monoclonal antibodies in plants."
According to the news reporters, the research concluded: "This article presents an overview of plant hybrid viral vector expression systems developed so far."
For more information on this research see: Hybrid Viral Vectors for Vaccine and Antibody Production in Plants. Current Pharmaceutical Design, 2013;19(31):5574-5586. Current Pharmaceutical Design can be contacted at: Bentham Science Publ Ltd, Executive Ste
Our news correspondents report that additional information may be obtained by contacting V. Yusibov, Fraunhofer,
Keywords for this news article include: Antibodies,
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2013, NewsRx LLC
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