By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- Infinity Pharmaceuticals, Inc. (NASDAQ: INFI) is observing National Blood Cancer Awareness Month, joining patients, healthcare providers and patient organizations in raising public awareness of blood cancers and the need for continued research for novel treatment options. In support of patients and their loved ones, Infinity is launching the Sparks of Inspiration campaign. Throughout the month of September, Infinity encourages the submission of stories along with photos or illustrations to honor friends, family members and loved ones affected by blood cancer. For each submission received, Infinity will make a donation of $10 to the Leukemia & Lymphoma Society (LLS), the world's largest voluntary health organization dedicated to blood cancers (see also Pharmaceutical Companies).
To learn more about Sparks of Inspiration and submit your tribute, please visit www.infi.com.
"We are grateful for the support from Infinity, which highlights our shared goal of advancing new treatment options for patients affected by blood cancers," said John Walter, president and CEO of LLS. "Blood Cancer Awareness Month is the right platform to create a sense of urgency about the need to continue investing in lifesaving treatments and cures. As there are no means of prevention of or early detection for most blood cancers, we must focus on cures."
"Infinity is committed to discovering and developing new medicines for patients with difficult-to-treat conditions, including blood cancers," commented Pedro Santabarbara, M.D., Ph.D. chief medical officer at Infinity. "Through this campaign, we are honoring the courage and strength of patients with blood cancers and their families. We are pleased to support the Leukemia & Lymphoma Society's mission of finding cures for blood cancers and improving the quality of life for patients and families."
Infinity is developing IPI-145, a potent, oral inhibitor of phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma, for the treatment of certain blood cancers.
"Early Phase 1 data of IPI-145 has shown encouraging signs of clinical activity across a broad range of blood cancers. I am excited to be involved in ongoing trials of IPI-145 and look forward to further evaluation of this investigational drug," said Ian Flinn, M.D., Ph.D., director, hematologic malignancies program, Sarah Cannon Research Institute, and an investigator for these clinical studies of IPI-145. "New targeted agents in development, such as IPI-145, have the potential not only to expand therapeutic options for patients but also to reduce or delay the need for chemotherapy."
The company is currently enrolling patients in a Phase 2 study (ClinicalTrials.gov Identifier NCT01882803) designed to evaluate the safety and efficacy of its lead product candidate, IPI-145, for the treatment of refractory indolent non-Hodgkin lymphoma (iNHL). Patients enrolled in this study must have progressed within six months of receiving their last therapy. Additionally, a Phase 1b investigator-sponsored trial of IPI-145 in patients with B-cell NHL, chronic lymphocytic leukemia (CLL) and T-cell lymphoma in combination with rituximab (a monoclonal antibody therapy), bendamustine (a chemotherapy) or both rituximab and bendamustine is also open for enrollment (NCT01871675). More About Sparks of InspirationInfinity encourages the submission of stories along with photos and illustrations honoring friends, family members or loved ones affected by blood cancer. For each submission received, Infinity will make a $10 donation to the Leukemia & Lymphoma Society, up to a total of $5,000. Submissions can be made through Infinity's website www.infi.com. Submissions will be accepted from September 3, 2013, through September 30, 2013. About the Development of IPI-145 for the Treatment of Blood CancersInfinity is developing IPI-145, a potent, oral inhibitor of Class I phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma. The PI3Ks are a family of enzymes involved in multiple cellular functions, including cell proliferation and survival, cell differentiation, cell migration and immunity.1 The PI3K-delta and PI3K-gamma isoforms are preferentially expressed in leukocytes (white blood cells), where they have distinct and mostly non-overlapping roles in immune cell development and function. Targeting PI3K-delta and PI3K-gamma may provide multiple opportunities to develop differentiated therapies for the treatment of hematologic malignancies as well as inflammatory diseases.
Keywords for this news article include: Infinity Pharmaceuticals Inc., Pharmaceutical Companies, Drugs, Cancer, Oncology, Treatment, Hematology, Chemotherapy, Leukemia Gene Therapy, Biotechnology Companies.
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