NEW YORK, NY -- (Marketwired) -- 08/30/13 -- A newly published prostate cancer study helps clarify the risk associated with watchful waiting and active surveillance. Researchers found that as prostate-specific antigen (PSA) testing became more widespread, late-stage prostate cancer diagnoses plummeted, but Gleason scores did not. Their findings suggest that men who choose not to treat their prostate cancer face greater danger of disease spread than disease strengthening.
Over the course of a 20-year data window (1982-2004), incidence of prostate-specific antigen (PSA) testing increased from 42 percent to 81 percent. During that time, late-stage prostate cancer diagnoses dropped 85 percent, but Gleason score declined a moderate 30 percent. Dr. David Samadi, expert robotic prostate surgeon and Chairman of Urology, Chief of Robotic Surgery at Lenox Hill Hospital and Professor of Urology at Hofstra North Shore-LIJ School of Medicine, explains the difference between prostate cancer staging and Gleason score.
"Prostate cancer staging is used to quantify disease spread within or beyond the prostate. Gleason score defines the cancer's aggressiveness or grade. Using PSA test results and biopsies, we attempt to define a man's overall disease as best we can," said Dr. Samadi.
Prostate cancer diagnosis can be challenging. The PSA test detects spikes in prostate-specific antigen levels that can indicate the presence of cancer. A prostate biopsy gives more data about disease characteristics, but experts admit it can be difficult to paint a complete picture.
"While data suggests untreated prostate cancer may not become more aggressive, it doesn't mean it will stay put," explains Dr. Samadi. "Left alone, prostate cancer is very likely to spread beyond the prostate. Robotic prostate surgery mitigates that risk by completely removing the cancerous prostate. If you wait till the cancer spreads, the opportunity for cure may be lost."
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