The study is being conducted at the
SEPREHVIR (HSV1716), is a variant of Herpes Simplex Virus 1 that has been engineered to kill cancer cells while leaving normal cells unharmed.
Malignant pleural mesothelioma (MPM) has a long latency (30-60 years from occupational exposure) and Virttu estimates that around 9,500 new cases of MPM occur each year in the US and the larger EU member states. Furthermore, the incidence is predicted to continue to rise in more recently industrialized nations, including
The first cohort of patients was treated with a single dose of SEPREHVIR. The treatment was well tolerated with no dose limiting toxicity or serious adverse events related to treatment. The current safety profile supports continued recruitment of patients into the second cohort, where patients will receive two doses, one week apart.
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