The award will support Dr. Barillot’s work in developing a database of cellular signaling pathways and a visualization tool to help the pharmaceutical industry develop more effective cancer treatments.
The new Web-based visualization tool will augment the institute’s Atlas of Cancer Signaling Networks and will be furtherenhanced by the combined capabilities of Curie’s NaviCell mapping tool and Agilent’s GeneSpring software and NMR technologies. Together, these tools will enable researchers to identify off-pathway effects that could lead to undesirable outcomes, such as DNA damage.
“Assessing the safety and potential toxicity of drug candidates is a significant hurdle in the extraordinarily complex, labor-intensive drug development process,” said
“The Agilent Thought Leader Award will accelerate the further development of the Curie Atlas of Cancer Signaling Networks, a comprehensive and freely available cancer pathway database, and NaviCell network visualization tool,” said Dr. Barillot. “These tools will enable earlier identification and visualization of toxic interactions between signaling pathways during the discovery and development of therapeutics for the treatment of cancer, thus enabling better informed drug-candidate selection and prioritization. They will also be useful for interpreting high-throughput biological data, like next-generation sequencing profiles of tumors or other samples.”
The Agilent Thought Leader program promotes fundamental scientific advances by contributing financial support, products and expertise to the research of influential thought leaders in the life sciences and chemical analysis. Information about previous award recipients is available at www.agilent.com/univ_relation/TLP/index.shtml.
About the Institut Curie
The Institut Curie comprises the largest oncology research center and two state-of-the-art hospitals in
Founded in 1909 on a model devised by
NOTE TO EDITORS: Further technology, corporate citizenship and executive news is available at www.agilent.com/go/news.
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