By a News Reporter-Staff News Editor at Gene Therapy Weekly -- Data detailed on Stem Cell Research have been presented. According to news reporting out of Dresden, Germany, by NewsRx editors, the research stated, "Stem cell research offers a wide variety of approaches for the advancement of our understanding of basic mechanisms of neurodegeneration and tissue regeneration and for the discovery and development of new therapeutic strategies to prevent and restore neuronal cell loss. Similar to most other regions of our central nervous system, degenerative diseases of the retina lead to the loss of neurons, which are not replaced."
Our news journalists obtained a quote from the research from Technical University, "Recent work in animals has provided proof-of-concept evidence for the restoration of photoreceptor cells by cell transplantation and neuronal cell replacement by regeneration from endogenous cell sources. However, efficient therapeutic prevention of neuronal cell loss has not been achieved. Moreover, successful cell replacement of retinal neurons in humans, including that of ganglion cells, remains a major challenge. Future successes in the discovery and translation of neuroprotective drug and gene therapies and of cell-based regenerative therapies will depend on a better understanding of the underlying disease pathomechanisms. Existing stem cell and cell-reprogramming technologies offer the potential to generate human retina cells, to develop specific human-cell-based retina disease models, and to open up novel therapeutic strategies. Further, we might glean substantial knowledge from species that can or cannot regenerate their neuronal retina, in the search for new therapeutic approaches. Thus, stem cell research will pave the way toward clinical translation."
According to the news editors, the research concluded: "In this review, I address some of the major possibilities presently on offer and speculate about the power of stem cell research to gain further insights into the pathomechanisms of retinal neurodegeneration (with special emphasis on glaucoma) and to advance our therapeutic options."
For more information on this research see: The potential of stem cell research for the treatment of neuronal damage in glaucoma. Cell and Tissue Research, 2013;353(2):311-325. Cell and Tissue Research can be contacted at: Springer, 233 Spring St, New York, NY 10013, USA. (Springer - www.springer.com; Cell and Tissue Research - www.springerlink.com/content/0302-766x/)
Our news journalists report that additional information may be obtained by contacting M.O. Karl, Technical University of Dresden, CRTD, D-01307 Dresden, Germany.
Keywords for this news article include: Biotechnology, Biomedical Engineering, Biomedicine, Europe, Dresden, Germany, Neurons, Glaucoma, Treatment, Eye Diseases, Gene Therapy, Therapeutics, Bioengineering, Stem Cell Research, Tissue Regeneration
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