By a News Reporter-Staff News Editor at Clinical Trials Week -- Investigators publish new report on Ophthalmology. According to news originating from Seoul, South Korea, by NewsRx correspondents, research stated, "To compare the rate of change of circumpapillary retinal nerve fiber layer (cRNFL) thickness, macular volume and thickness, and optic nerve head (ONH) parameters assessed using spectral-domain optical coherence tomography (SD-OCT) between eyes with progressing and nonprogressing glaucoma. Longitudinal, observational study."
Our news journalists obtained a quote from the research from the University of Ulsan, "Two hundred seventy-nine eyes from 162 glaucoma patients followed for an average of 2.2 years. Eyes were classified as progressors and nonprogressors according to assessment of optic disc and RNFL photographs and visual field progression analysis. Linear mixed effects models were used to evaluate the overall rate of change of cRNFL thickness, macular volume and thickness, and ONH parameters after adjustment for age, spherical equivalent, signal strength, and baseline SD-OCT measurements. The rate of change of cRNFL thickness, macular volume, and thickness and ONH parameters. Sixty-three eyes (22.6%) from 52 subjects were identified as progressors. Average, inferior quadrant, and 6- and 7-o'clock sector cRNFL thickness decreased faster in progressors than in nonprogressors (-1.26 vs -0.94, -2.47 vs -1.75, -3.60 vs -2.52, and -2.77 vs -1.51 mu m/year, respectively; all P
According to the news editors, the research concluded: "Serial measurement of parameters in all 3 areas (cRNFL, macula, and ONH) by SD-OCT may permit identification of progression in glaucomatous eyes."
For more information on this research see: Detection of Glaucomatous Progression by Spectral-Domain Optical Coherence Tomography. Ophthalmology, 2013;120(7):1388-1395. Ophthalmology can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; Ophthalmology - www.elsevier.com/wps/product/cws_home/620418)
The news correspondents report that additional information may be obtained from J.H. Na, University of Ulsan, Asan Med Center, Coll Med, Dept. of Clin Epidemiol & Biostat, Seoul 138736, South Korea. Additional authors for this research include K.R. Sung, J.R. Lee, K.S. Lee, S. Baek, H.K. Kim and Y.H. Sohn (see also Ophthalmology).
Keywords for this news article include: Asia, Seoul, South Korea, Ophthalmology, Imaging Technology, Clinical Trials and Studies, Optical Coherence Tomography
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