By a News Reporter-Staff News Editor at Drug Week -- A new study on Pharmaceutical Research is now available. According to news reporting from Zhengzhou, People's Republic of China, by NewsRx journalists, research stated, "The purpose of the present study was to develop a novel transdermal vinpocetine patch containing a stable formulation and with good entrapment efficiency, and percutaneous absorption which via ethosome. Ethosome was found to be a more efficient delivery carrier with high encapsulation capacities (79.5% ±1.8%) and nanometric size (180.7 ±1.5 nm)."
The news correspondents obtained a quote from the research from Zhengzhou University, "In vitro percutaneous permeation experiments demonstrated that the permeation of vinpocetine through abdominal skin of Sprague Dawley was significantly increased when ethosome was used. The vinpocetine transdermal fluxes from ethosome gel (3.56 ±0.13 microg/cm2/h) were 6.72 and 3.10 times higher than that of vinpocetine gel solution and vinpocetine aueous solution, respectively. Furthermore, the AUC(0 -- >infinity), and eliminiation half-life by the transdermal administration were significantly higher than those by the intragastric administration (p
According to the news reporters, the research concluded: "The study demonstrated that ethosome is a promising vesicular carrier for enhancing percutaneous absorption of vinpocetine."
For more information on this research see: Ethosomes as delivery system for transdermal administration of vinpocetine. Pharmazie, 2013;68(5):381-2. Pharmazie can be contacted at: Govi-Verlag GmbH, Pharmazeutischer Verlag Ginnheimer Strasse 26, D-65760 Eschborn, Germany. (Wiley-Blackwell - www.wiley.com/; Pharmazie - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1615-1003)
Our news journalists report that additional information may be obtained by contacting Y.T. Mao, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, People's Taiwan. Additional authors for this research include H.Y. Hua, X.G. Zhang, D.X. Zhu, F. Li, Z.H. Gui and Y.X Zhao (see also Pharmaceutical Research).
Publisher contact information for the journal Pharmazie is: Govi-Verlag GmbH, Pharmazeutischer Verlag Ginnheimer Strasse 26, D-65760 Eschborn, Germany.
Keywords for this news article include: Asia, Pharmaceutical Research, Zhengzhou, People's Republic of China.
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