House Research Institute and Children’s Hospital Los Angeles to
Collaborate on Federally Funded Study Intended to Restore Hearing to
LOS ANGELES--(BUSINESS WIRE)--
House Research Institute (HRI) and Children’s Hospital Los Angeles
announced today final approval of grant funding by the National
Institutes of Health (NIH) National Institute on Deafness and
Communications Disorders (NIDCD) for a major five-year, FDA-approved
clinical trial of the auditory brainstem implant (ABI) in children.
Children's Hospital Los Angeles Chief of Medical Staff Mark Krieger, MD, head of the hospital's Neurosurgery division and Billy and Audrey Wilder Endowed Chair in Neurosurgery, will be part of the surgical team in a new clinical trial on the auditory brainstem implant for children. (Photo: Business Wire)
“We are grateful to the NIDCD for funding our study at House/Children’s
Hospital, which represents the first time the NIDCD has funded a
pediatric ABI clinical trial,” said Eric P. Wilkinson, MD, co-principal
investigator, House Research Institute, lead physician on the study, and
associate, House Clinic.
Marc S. Schwartz, M.D., ABI neurosurgeon and investigator, and
neurosurgeon at House Neurosurgical Associates at the House Clinic,
agreed. “The clinical trial grant provides us with vital funding to
begin phase one of our surgical trial of the pediatric ABI in the U.S.”
Mark Krieger, M.D., pediatric neurosurgeon and chief of medical staff,
Children’s Hospital Los Angeles, and Billy and Audrey Wilder Endowed
Chair in Neurosurgery, completes the surgical team. Study surgeries will
be performed at the Children’s Hospital. “We are extremely excited to
bring this revolutionary technology to Children’s Hospital. We are
especially looking forward to offering this innovative procedure to
provide sound to deaf children in the United States,” Krieger said.
Children considered for the clinical trial must have congenital
bilateral deafness resulting from a malformed or non-existent cochlea or
hearing nerve. Such patients cannot receive hearing benefits from a
hearing aid or cochlear implant. Children with cochlear implants that
have not provided benefit are also suitable candidates for the study.
Ten U.S. children will have their surgical and audiological care
provided by the trial grant.
The ABI was developed at HRI in the late 1970s and is the world’s first
successful prosthetic hearing device to stimulate neurons directly at
the human brainstem, bypassing the inner ear and hearing nerve entirely.
More than 1,000 adults worldwide have received the ABI, led by
physicians of the House Clinic.