The assignee for this patent, patent number 8486708, is
Reporters obtained the following quote from the background information supplied by the inventors: "Development of sensors or probes that can be used to detect the trace vapor of organic amines represents one of the active research fields in chemistry and materials science, particularly those related to the emerging nanoscience and nanotechnology. Volatile amines have been heavily used in various areas ranging from chemical and pharmaceutical to food industries. Some of the amines, like hydrazine, have also been used in the military as fuel additives in rocket and fighter jet propulsion systems. Detecting these amines with high sensitivity is not only critical to air pollution monitoring and control but also may provide expedient ways for quality control of food and even medical diagnosis of certain types of disease. For example, in diagnosing uremia and lung cancer, released biogenic amines are commonly used as biomarkers.
"Although much success has been achieved for detection of amines in solutions using various types of sensors, the vapor-based detection of gaseous amines still remains challenging. This challenge is largely due to the limited availability of sensory materials that enable vapor detection with both high sensitivity and selectivity. Fluorescent sensing and probing based on organic sensory materials represents a unique class of detection techniques that usually provide a simple, expedient way for chemical detection and analysis. However, there are not many organic materials available that are sufficiently fluorescent in the solid state and suited for use as sensory materials in vapor detection. These materials may be strongly fluorescent in molecular state in solutions. Moreover, compared to the more common p-type (i.e., electron donating) materials, which are suited for sensing oxidative reagents like nitro-based compounds, the availability of n-type organic materials (i.e., electron accepting, and suited for sensing reducing reagents like amines) is much more limited."
In addition to obtaining background information on this patent, VerticalNews editors also obtained the inventors' summary information for this patent: "In light of the problems and deficiencies noted above, fluorescent sensor compounds for detecting amines can be 3,4,9,10-tetracarboxyl perylene compounds having the formula I:
"where A and A' are independently chosen from N--R1, N--R2, and O such that both A and A' are not O, and R1 through R10 are amine binding moieties, solubility enhancing groups, or hydrogen such that at least one of R1 through R10 is an amine binding moiety. Typically, the fluorescent sensor compounds can be formed into a nanofiber structure although this is not required.
"A nanofiber-based fluorescent sensor compound can be formed via synthesis of the underlying perylene compound which is then formed into the nanofibers. For example, a 3,4,9,10-tetracarboxyl perylene compound having the Formula I (as previously noted) can be synthesized. The perylene compound can be self-assembled into nanofibers via any suitable process such as, but not limited to, a slow controlled solvent-exchange step, rapid solution dispersion, phase transfer at the interface between two solvents, sol-gel processing, direct vaporization of the solvent, or any other suitable self-assembly methods including the surface assisted process. The nanofiber fluorescent sensor compound can optionally be formed into a film of entangled nanofibers by coating the nanofiber dispersion on a substrate.
"There has thus been outlined, rather broadly, the more important features of the invention so that the detailed description thereof that follows may be better understood, and so that the present contribution to the art may be better appreciated. Other features of the present invention will become clearer from the following detailed description of the invention, taken with the accompanying figures and claims, or may be learned by the practice of the invention."
For more information, see this patent: Zang, Ling; Che,
Keywords for this news article include: Amines, Nanofiber, Nanotechnology, Organic Chemicals, Emerging Technologies,
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