IRVINE, CA -- (Marketwired) -- 07/15/13 -- MRI Interventions, Inc. (OTCQB: MRIC) today announced the presentation of data and results indicating the benefits of its ClearPoint® Neuro Intervention System as a platform for iMRI-guided deep brain stimulation (DBS) lead placement in pediatric patients. A research team led by Dr. Philip Starr (neurosurgeon) and Dr. Jill Ostrem (neurologist) from the University of California, San Francisco (UCSF) presented an abstract at the 2013 International Congress of Parkinson's Disease and Movement Disorders in Sydney, Australia outlining data collected from the treatment and post-operative follow up of six children with pediatric primary dystonia who underwent iMRI-guided DBS procedures with the ClearPoint system. Leslie Markun, MSc, lead author on the abstract, showed that iMRI-guided DBS surgery, which allows patients to sleep through the procedure, is a technically simple and accurate option for a patient population that traditionally exhibits a low tolerance for conventional awake DBS surgery. The UCSF team plans to submit its findings for publication in a peer-reviewed journal.
Highlights of the presentation included:
•Only a single brain penetration was used for placement of the DBS leads; •The average accuracy of the lead placement was under one millimeter; •The average surgical time for lead placement was just over three hours; •At 12 months follow up, the patients' movement scores improved an average of 88% on the Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS); •Clinical outcomes were comparable to the best reported outcomes that have been achieved using traditional methods.
"The data from this study suggest that 'asleep DBS' can be performed extremely accurately when guided by ClearPoint," said Philip A. Starr, MD, PhD, at UCSF, who collaborated with MRI Interventions in developing the iMRI procedure, but holds no intellectual property rights to it. "The clinical outcomes indicate that this is an excellent surgical method in children, and on a MRI system providing high resolution imaging, the procedure is straightforward to perform."
Deep brain stimulation surgery for children has long presented a challenge to stereotactic neurosurgeons because the procedure traditionally has required patients to remain awake and provide feedback to help confirm accurate placement of the DBS leads. Children often have not been considered good candidates for DBS surgery due to this requirement.
IMRI-guided surgery with the ClearPoint system opens up the possibility of DBS as a treatment option for these children by allowing patients to undergo an "asleep DBS" procedure. Using the ClearPoint system, a surgeon can see, in real time, the inside of a patient's brain and the location of surgical tools and devices, which can eliminate the need for a patient's conscious feedback. The ClearPoint system easily integrates with a hospital's existing MRI scanner, which is ideal for real-time imaging throughout surgery because it provides high-quality visualization of the soft tissue of the brain and does not expose patients to ionizing radiation, unlike other imaging methods such as computed tomography (CT) and X-ray. In addition to DBS lead placement, the ClearPoint system can be used as a delivery platform for neurological therapies and interventions such as focal laser ablation, brain biopsy, and drug delivery.
Most Popular Stories
- 5 Potential Snags to the Bipartisan Budget Deal
- Sonoma Growers Win Emerald Cup Cannabis Competition
- Rubio Offers Endorsements, Cash to 2014 GOP Candidates
- Phil Pustejovsky's Relief Real Estate Offers Seminars in Daytona Beach
- Cantor Fitzgerald Settles Suit
- GM Plant Tackles Tough Waste Challenge
- Legal Dope in Uruguay Breaks International Law, Says Buzzkill U.N.
- Pope Removes U.S. Archbishop from Powerful Post
- 'New Rich' May Be Barrier to Bridging Income Gap
- Researchers Question Effectiveness of Vitamins